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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP3B1 All Species: 29.39
Human Site: S200 Identified Species: 64.67
UniProt: O00203 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00203 NP_003655.3 1094 121320 S200 E K L L K D K S T L V A G S V
Chimpanzee Pan troglodytes XP_517689 1094 121238 S200 E K L L K D K S T L V A G S V
Rhesus Macaque Macaca mulatta XP_001082529 1112 122383 T195 E K L L A D K T T L V A G S V
Dog Lupus familis XP_860622 983 108630 I154 C P E R I D L I H K N Y R K L
Cat Felis silvestris
Mouse Mus musculus Q9Z1T1 1105 122852 S200 E K L L K D K S T L V A G S V
Rat Rattus norvegicus P62944 937 104534 R108 L I R A L A V R T M G C I R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514251 1221 135515 S307 E K L L K D K S T L V A G S V
Chicken Gallus gallus XP_001232605 1113 123005 T224 E K L L A D K T T L V A G S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525071 1160 127118 T201 E K L L S D R T T L V V G S A
Honey Bee Apis mellifera XP_624446 1049 117649 T202 E K L L S D K T T L V V G S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P46682 809 91589
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 63.2 59.3 N.A. 86.8 23.7 N.A. 74.2 62.7 N.A. N.A. N.A. 49.6 53.2 N.A. N.A.
Protein Similarity: 100 99.8 75.5 71.7 N.A. 91.6 43.2 N.A. 80.4 76.3 N.A. N.A. N.A. 66.8 68.8 N.A. N.A.
P-Site Identity: 100 100 86.6 6.6 N.A. 100 13.3 N.A. 100 86.6 N.A. N.A. N.A. 66.6 73.3 N.A. N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 100 20 N.A. 100 93.3 N.A. N.A. N.A. 80 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 19 10 0 0 0 0 0 55 0 0 19 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 % D
% Glu: 73 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 73 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 0 0 10 0 0 0 0 10 0 0 % I
% Lys: 0 73 0 0 37 0 64 0 0 10 0 0 0 10 0 % K
% Leu: 10 0 73 73 10 0 10 0 0 73 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 10 0 0 10 10 0 0 0 0 10 10 0 % R
% Ser: 0 0 0 0 19 0 0 37 0 0 0 0 0 73 0 % S
% Thr: 0 0 0 0 0 0 0 37 82 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 73 19 0 0 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _