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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B1
All Species:
31.52
Human Site:
S374
Identified Species:
69.33
UniProt:
O00203
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00203
NP_003655.3
1094
121320
S374
M
F
E
P
Y
L
K
S
F
Y
V
R
S
T
D
Chimpanzee
Pan troglodytes
XP_517689
1094
121238
S374
M
F
E
P
Y
L
K
S
F
Y
V
R
S
T
D
Rhesus Macaque
Macaca mulatta
XP_001082529
1112
122383
S379
M
F
E
P
Y
L
K
S
F
Y
I
R
S
T
D
Dog
Lupus familis
XP_860622
983
108630
F314
I
P
T
V
L
R
E
F
Q
T
Y
I
R
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T1
1105
122852
S375
M
F
E
P
Y
L
K
S
F
Y
V
R
S
T
D
Rat
Rattus norvegicus
P62944
937
104534
E268
K
V
L
M
K
F
L
E
L
L
P
K
D
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
S482
T
F
E
P
Y
L
K
S
F
Y
V
R
S
T
D
Chicken
Gallus gallus
XP_001232605
1113
123005
S405
M
F
E
P
Y
L
K
S
F
Y
I
R
S
T
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
S410
I
F
E
P
H
L
K
S
F
F
V
R
T
S
D
Honey Bee
Apis mellifera
XP_624446
1049
117649
S372
M
F
E
P
F
L
K
S
F
F
V
R
T
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
L139
S
E
L
R
C
F
A
L
S
A
L
S
D
M
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
63.2
59.3
N.A.
86.8
23.7
N.A.
74.2
62.7
N.A.
N.A.
N.A.
49.6
53.2
N.A.
N.A.
Protein Similarity:
100
99.8
75.5
71.7
N.A.
91.6
43.2
N.A.
80.4
76.3
N.A.
N.A.
N.A.
66.8
68.8
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
66.6
73.3
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
20
N.A.
93.3
100
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
82
% D
% Glu:
0
10
73
0
0
0
10
10
0
0
0
0
0
0
0
% E
% Phe:
0
73
0
0
10
19
0
10
73
19
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
0
0
19
10
0
0
0
% I
% Lys:
10
0
0
0
10
0
73
0
0
0
0
10
0
0
10
% K
% Leu:
0
0
19
0
10
73
10
10
10
10
10
0
0
0
0
% L
% Met:
55
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
73
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
0
73
10
0
0
% R
% Ser:
10
0
0
0
0
0
0
73
10
0
0
10
55
37
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
10
0
0
19
55
0
% T
% Val:
0
10
0
10
0
0
0
0
0
0
55
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
55
0
0
0
0
55
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _