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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP3B1 All Species: 10.91
Human Site: S790 Identified Species: 24
UniProt: O00203 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00203 NP_003655.3 1094 121320 S790 E S E S E P E S E S E S R R V
Chimpanzee Pan troglodytes XP_517689 1094 121238 S790 E S E S E P E S E S E S R R V
Rhesus Macaque Macaca mulatta XP_001082529 1112 122383 E795 S S S T S E S E M T S E S E E
Dog Lupus familis XP_860622 983 108630 V703 P S S K S A P V A K E I S L L
Cat Felis silvestris
Mouse Mus musculus Q9Z1T1 1105 122852 S801 E S E S G S D S E P A P R N V
Rat Rattus norvegicus P62944 937 104534 G657 M G A V D L L G G G L D S L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514251 1221 135515 V898 S D L E S R K V I K E Q K K T
Chicken Gallus gallus XP_001232605 1113 123005 K821 A P T V V E A K R R K V I P S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525071 1160 127118 S827 S S A Y S G S S S D D S A S G
Honey Bee Apis mellifera XP_624446 1049 117649 T765 S K E T K Y K T L N E E A K E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P46682 809 91589 V529 E F K I C P D V L R R L I Q N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 63.2 59.3 N.A. 86.8 23.7 N.A. 74.2 62.7 N.A. N.A. N.A. 49.6 53.2 N.A. N.A.
Protein Similarity: 100 99.8 75.5 71.7 N.A. 91.6 43.2 N.A. 80.4 76.3 N.A. N.A. N.A. 66.8 68.8 N.A. N.A.
P-Site Identity: 100 100 6.6 13.3 N.A. 53.3 6.6 N.A. 6.6 0 N.A. N.A. N.A. 20 13.3 N.A. N.A.
P-Site Similarity: 100 100 20 20 N.A. 60 13.3 N.A. 26.6 6.6 N.A. N.A. N.A. 26.6 53.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 0 0 10 10 0 10 0 10 0 19 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 19 0 0 10 10 10 0 0 0 % D
% Glu: 37 0 37 10 19 19 19 10 28 0 46 19 0 10 19 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 10 0 10 10 10 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 10 0 0 10 19 0 0 % I
% Lys: 0 10 10 10 10 0 19 10 0 19 10 0 10 19 0 % K
% Leu: 0 0 10 0 0 10 10 0 19 0 10 10 0 19 10 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 10 % N
% Pro: 10 10 0 0 0 28 10 0 0 10 0 10 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % Q
% Arg: 0 0 0 0 0 10 0 0 10 19 10 0 28 19 0 % R
% Ser: 37 55 19 28 37 10 19 37 10 19 10 28 28 10 10 % S
% Thr: 0 0 10 19 0 0 0 10 0 10 0 0 0 0 10 % T
% Val: 0 0 0 19 10 0 0 28 0 0 0 10 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _