KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B1
All Species:
5.45
Human Site:
S817
Identified Species:
12
UniProt:
O00203
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00203
NP_003655.3
1094
121320
S817
T
P
L
T
K
D
V
S
L
L
D
L
D
D
F
Chimpanzee
Pan troglodytes
XP_517689
1094
121238
S817
T
P
L
T
K
D
V
S
L
L
D
L
D
D
F
Rhesus Macaque
Macaca mulatta
XP_001082529
1112
122383
P822
P
P
S
S
K
R
A
P
A
T
K
E
I
S
L
Dog
Lupus familis
XP_860622
983
108630
S730
V
S
P
P
T
I
V
S
T
S
L
A
T
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T1
1105
122852
F828
H
P
P
S
K
D
V
F
L
L
D
L
D
D
F
Rat
Rattus norvegicus
P62944
937
104534
A684
F
A
P
S
P
T
P
A
V
V
S
S
G
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
F925
S
L
L
D
L
D
D
F
N
S
V
S
T
P
V
Chicken
Gallus gallus
XP_001232605
1113
123005
P848
L
D
D
F
T
P
P
P
P
Q
P
V
P
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
K854
D
T
G
T
K
P
E
K
L
K
E
K
H
E
K
Honey Bee
Apis mellifera
XP_624446
1049
117649
P792
D
D
V
I
P
M
T
P
I
M
P
L
S
T
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
L556
L
V
L
S
A
K
L
L
S
Y
D
I
D
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
63.2
59.3
N.A.
86.8
23.7
N.A.
74.2
62.7
N.A.
N.A.
N.A.
49.6
53.2
N.A.
N.A.
Protein Similarity:
100
99.8
75.5
71.7
N.A.
91.6
43.2
N.A.
80.4
76.3
N.A.
N.A.
N.A.
66.8
68.8
N.A.
N.A.
P-Site Identity:
100
100
13.3
20
N.A.
73.3
0
N.A.
13.3
0
N.A.
N.A.
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
80
26.6
N.A.
20
6.6
N.A.
N.A.
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
10
10
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
19
10
10
0
37
10
0
0
0
37
0
37
37
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
10
0
10
0
% E
% Phe:
10
0
0
10
0
0
0
19
0
0
0
0
0
0
37
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
10
0
0
10
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
46
10
0
10
0
10
10
10
0
0
10
% K
% Leu:
19
10
37
0
10
0
10
10
37
28
10
37
0
10
19
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% N
% Pro:
10
37
28
10
19
19
19
28
10
0
19
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
37
0
0
0
28
10
19
10
19
10
19
10
% S
% Thr:
19
10
0
28
19
10
10
0
10
10
0
0
19
10
0
% T
% Val:
10
10
10
0
0
0
37
0
10
10
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _