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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B1
All Species:
26.67
Human Site:
T254
Identified Species:
58.67
UniProt:
O00203
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00203
NP_003655.3
1094
121320
T254
M
L
T
R
Y
A
R
T
Q
F
V
S
P
W
K
Chimpanzee
Pan troglodytes
XP_517689
1094
121238
T254
M
L
T
R
Y
A
R
T
Q
F
V
S
P
W
K
Rhesus Macaque
Macaca mulatta
XP_001082529
1112
122383
T249
M
L
T
R
Y
A
R
T
Q
F
L
S
P
T
Q
Dog
Lupus familis
XP_860622
983
108630
P195
F
L
S
P
T
Q
N
P
Y
V
M
D
P
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T1
1105
122852
T254
M
L
T
R
Y
A
R
T
Q
F
V
S
P
W
R
Rat
Rattus norvegicus
P62944
937
104534
H149
A
V
C
V
A
K
L
H
D
I
N
A
Q
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
T361
M
L
T
R
Y
A
R
T
Q
F
V
S
P
W
K
Chicken
Gallus gallus
XP_001232605
1113
123005
T278
M
L
T
R
Y
A
R
T
Q
F
L
S
P
N
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
T255
M
L
T
R
Y
A
R
T
Q
F
V
D
P
N
A
Honey Bee
Apis mellifera
XP_624446
1049
117649
Y253
I
V
N
M
L
T
R
Y
A
R
T
Q
F
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
R20
D
T
A
K
V
I
T
R
E
A
A
A
V
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
63.2
59.3
N.A.
86.8
23.7
N.A.
74.2
62.7
N.A.
N.A.
N.A.
49.6
53.2
N.A.
N.A.
Protein Similarity:
100
99.8
75.5
71.7
N.A.
91.6
43.2
N.A.
80.4
76.3
N.A.
N.A.
N.A.
66.8
68.8
N.A.
N.A.
P-Site Identity:
100
100
80
13.3
N.A.
93.3
0
N.A.
100
80
N.A.
N.A.
N.A.
80
6.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
100
13.3
N.A.
100
93.3
N.A.
N.A.
N.A.
80
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
64
0
0
10
10
10
19
0
10
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
0
19
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
64
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
10
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
28
% K
% Leu:
0
73
0
0
10
0
10
0
0
0
19
0
0
0
0
% L
% Met:
64
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
10
0
0
19
10
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
0
0
73
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
64
0
0
10
10
0
19
% Q
% Arg:
0
0
0
64
0
0
73
10
0
10
0
0
0
0
10
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
55
0
0
0
% S
% Thr:
0
10
64
0
10
10
10
64
0
0
10
0
0
10
10
% T
% Val:
0
19
0
10
10
0
0
0
0
10
46
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
37
0
% W
% Tyr:
0
0
0
0
64
0
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _