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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B1
All Species:
21.52
Human Site:
T621
Identified Species:
47.33
UniProt:
O00203
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00203
NP_003655.3
1094
121320
T621
R
D
H
F
Q
L
G
T
L
S
H
T
L
N
I
Chimpanzee
Pan troglodytes
XP_517689
1094
121238
T621
R
D
H
F
Q
L
G
T
L
S
H
T
L
N
I
Rhesus Macaque
Macaca mulatta
XP_001082529
1112
122383
S626
R
D
H
F
Q
L
G
S
L
S
H
L
L
N
A
Dog
Lupus familis
XP_860622
983
108630
K534
L
S
H
L
L
N
A
K
A
T
G
Y
Q
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T1
1105
122852
S632
H
T
L
N
I
K
A
S
G
Y
L
E
L
S
N
Rat
Rattus norvegicus
P62944
937
104534
I488
Q
L
T
L
L
T
A
I
V
K
L
F
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
T729
R
D
H
F
Q
L
G
T
L
S
H
T
L
N
T
Chicken
Gallus gallus
XP_001232605
1113
123005
S652
R
D
H
F
Q
L
G
S
L
S
H
L
L
N
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
S658
G
N
N
F
Q
L
G
S
L
S
H
Y
L
N
M
Honey Bee
Apis mellifera
XP_624446
1049
117649
I596
L
P
Q
L
A
K
R
I
F
L
A
P
K
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
L360
Q
G
N
K
E
M
L
L
Q
A
I
H
F
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
63.2
59.3
N.A.
86.8
23.7
N.A.
74.2
62.7
N.A.
N.A.
N.A.
49.6
53.2
N.A.
N.A.
Protein Similarity:
100
99.8
75.5
71.7
N.A.
91.6
43.2
N.A.
80.4
76.3
N.A.
N.A.
N.A.
66.8
68.8
N.A.
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
6.6
6.6
N.A.
93.3
80
N.A.
N.A.
N.A.
60
0
N.A.
N.A.
P-Site Similarity:
100
100
86.6
20
N.A.
20
20
N.A.
93.3
86.6
N.A.
N.A.
N.A.
86.6
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
28
0
10
10
10
0
0
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% E
% Phe:
0
0
0
55
0
0
0
0
10
0
0
10
10
0
0
% F
% Gly:
10
10
0
0
0
0
55
0
10
0
10
0
0
0
0
% G
% His:
10
0
55
0
0
0
0
0
0
0
55
10
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
19
0
0
10
0
0
0
19
% I
% Lys:
0
0
0
10
0
19
0
10
0
10
0
0
10
10
10
% K
% Leu:
19
10
10
28
19
55
10
10
55
10
19
19
73
10
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
19
10
0
10
0
0
0
0
0
0
0
55
10
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
19
0
10
0
55
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
46
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
37
0
55
0
0
0
10
10
% S
% Thr:
0
10
10
0
0
10
0
28
0
10
0
28
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _