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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B1
All Species:
11.21
Human Site:
Y274
Identified Species:
24.67
UniProt:
O00203
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00203
NP_003655.3
1094
121320
Y274
E
D
N
G
K
N
F
Y
E
S
D
D
D
Q
K
Chimpanzee
Pan troglodytes
XP_517689
1094
121238
Y274
E
D
N
G
K
N
F
Y
E
S
D
D
D
Q
K
Rhesus Macaque
Macaca mulatta
XP_001082529
1112
122383
G279
S
E
E
D
E
A
K
G
A
G
S
E
E
T
A
Dog
Lupus familis
XP_860622
983
108630
Q214
R
N
T
K
P
L
L
Q
S
R
S
A
A
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T1
1105
122852
E275
D
N
E
K
N
F
Y
E
S
E
E
E
E
E
E
Rat
Rattus norvegicus
P62944
937
104534
L168
F
L
D
S
L
R
D
L
I
A
D
S
N
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
Y382
E
N
N
E
K
N
F
Y
E
S
D
D
E
Q
Q
Chicken
Gallus gallus
XP_001232605
1113
123005
D305
F
Y
G
S
E
E
E
D
T
K
D
A
K
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
N310
K
S
S
T
N
N
K
N
N
G
G
G
N
G
S
Honey Bee
Apis mellifera
XP_624446
1049
117649
R272
N
I
E
D
D
E
N
R
P
F
Y
D
S
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
S39
E
S
S
Y
T
Y
Y
S
Q
N
I
N
P
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
63.2
59.3
N.A.
86.8
23.7
N.A.
74.2
62.7
N.A.
N.A.
N.A.
49.6
53.2
N.A.
N.A.
Protein Similarity:
100
99.8
75.5
71.7
N.A.
91.6
43.2
N.A.
80.4
76.3
N.A.
N.A.
N.A.
66.8
68.8
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
0
6.6
N.A.
73.3
6.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
26.6
6.6
N.A.
53.3
26.6
N.A.
93.3
20
N.A.
N.A.
N.A.
26.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
10
10
0
19
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
10
19
10
0
10
10
0
0
46
37
19
10
0
% D
% Glu:
37
10
28
10
19
19
10
10
28
10
10
19
28
10
19
% E
% Phe:
19
0
0
0
0
10
28
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
10
19
0
0
0
10
0
19
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
10
0
0
19
28
0
19
0
0
10
0
0
10
0
19
% K
% Leu:
0
10
0
0
10
10
10
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
28
28
0
19
37
10
10
10
10
0
10
19
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
10
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
0
37
19
% Q
% Arg:
10
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% R
% Ser:
10
19
19
19
0
0
0
10
19
28
19
10
10
0
19
% S
% Thr:
0
0
10
10
10
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
10
19
28
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _