KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3B1
All Species:
18.18
Human Site:
Y593
Identified Species:
40
UniProt:
O00203
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00203
NP_003655.3
1094
121320
Y593
K
S
G
A
L
S
K
Y
A
K
K
I
F
L
A
Chimpanzee
Pan troglodytes
XP_517689
1094
121238
Y593
K
S
G
A
L
S
K
Y
A
K
K
I
F
L
A
Rhesus Macaque
Macaca mulatta
XP_001082529
1112
122383
H598
Q
G
G
A
L
S
R
H
A
K
K
L
F
L
A
Dog
Lupus familis
XP_860622
983
108630
K507
K
K
L
F
L
A
P
K
P
A
P
V
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T1
1105
122852
Y594
K
S
G
A
L
S
K
Y
A
K
K
I
F
L
A
Rat
Rattus norvegicus
P62944
937
104534
N461
E
Y
A
E
R
I
D
N
A
D
E
L
L
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514251
1221
135515
Y701
K
S
G
A
L
S
K
Y
A
K
K
I
F
L
A
Chicken
Gallus gallus
XP_001232605
1113
123005
Y624
K
S
G
A
L
N
K
Y
A
K
K
L
F
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525071
1160
127118
Q629
G
T
S
S
V
L
S
Q
H
A
R
Q
V
F
L
Honey Bee
Apis mellifera
XP_624446
1049
117649
R569
Y
D
Q
N
Y
D
I
R
D
R
A
R
F
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46682
809
91589
Q333
Y
Q
L
A
S
P
L
Q
M
K
N
T
K
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
63.2
59.3
N.A.
86.8
23.7
N.A.
74.2
62.7
N.A.
N.A.
N.A.
49.6
53.2
N.A.
N.A.
Protein Similarity:
100
99.8
75.5
71.7
N.A.
91.6
43.2
N.A.
80.4
76.3
N.A.
N.A.
N.A.
66.8
68.8
N.A.
N.A.
P-Site Identity:
100
100
66.6
13.3
N.A.
100
6.6
N.A.
100
86.6
N.A.
N.A.
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
100
33.3
N.A.
100
100
N.A.
N.A.
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
64
0
10
0
0
64
19
10
0
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
10
0
10
10
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
0
0
0
0
0
10
0
0
19
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
64
19
0
% F
% Gly:
10
10
55
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
37
0
0
10
% I
% Lys:
55
10
0
0
0
0
46
10
0
64
55
0
10
0
0
% K
% Leu:
0
0
19
0
64
10
10
0
0
0
0
28
19
64
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
10
0
10
0
0
0
0
% P
% Gln:
10
10
10
0
0
0
0
19
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
10
0
10
10
0
10
10
10
0
0
10
% R
% Ser:
0
46
10
10
10
46
10
0
0
0
0
0
0
0
19
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
10
0
0
10
0
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _