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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APBB1 All Species: 13.64
Human Site: S666 Identified Species: 33.33
UniProt: O00213 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00213 NP_001155.1 710 77244 S666 Q K C L D A R S Q A S T S C L
Chimpanzee Pan troglodytes XP_521814 848 91186 S804 Q K C L D A R S Q A S T S C L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534037 724 78741 A681 V R F L S F L A V G R D V H T
Cat Felis silvestris
Mouse Mus musculus Q9QXJ1 710 77450 S666 Q K C L D A R S Q T S T S C L
Rat Rattus norvegicus P46933 711 77638 S667 Q K C L D A R S Q T S T S C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507097 616 68316 S573 C L V A R P P S Q K V Q P P P
Chicken Gallus gallus XP_420735 740 81441 P696 Q K C L V A R P P S Q K V R P
Frog Xenopus laevis NP_001087003 610 66956 P567 Q K C L D G R P Q G S S C L P
Zebra Danio Brachydanio rerio XP_693392 869 95380 P824 Q K C L V A R P P S Q K A C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787988 848 93773 G781 K M N L I S S G R F L L R V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 N.A. 78.3 N.A. 94.6 93.8 N.A. 38.8 45 51.5 39.5 N.A. N.A. N.A. N.A. 31
Protein Similarity: 100 83.7 N.A. 80.6 N.A. 97.1 96 N.A. 53.6 60.9 62.2 53.5 N.A. N.A. N.A. N.A. 47.1
P-Site Identity: 100 100 N.A. 6.6 N.A. 93.3 93.3 N.A. 13.3 40 53.3 46.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 20 N.A. 93.3 93.3 N.A. 13.3 46.6 60 60 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 60 0 10 0 20 0 0 10 0 0 % A
% Cys: 10 0 70 0 0 0 0 0 0 0 0 0 10 50 0 % C
% Asp: 0 0 0 0 50 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 10 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 20 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 70 0 0 0 0 0 0 0 10 0 20 0 0 0 % K
% Leu: 0 10 0 90 0 0 10 0 0 0 10 10 0 10 40 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 10 30 20 0 0 0 10 10 30 % P
% Gln: 70 0 0 0 0 0 0 0 60 0 20 10 0 0 0 % Q
% Arg: 0 10 0 0 10 0 70 0 10 0 10 0 10 10 0 % R
% Ser: 0 0 0 0 10 10 10 50 0 20 50 10 40 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 20 0 40 0 0 20 % T
% Val: 10 0 10 0 20 0 0 0 10 0 10 0 20 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _