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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APBB1 All Species: 15.15
Human Site: S669 Identified Species: 37.04
UniProt: O00213 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00213 NP_001155.1 710 77244 S669 L D A R S Q A S T S C L P A P
Chimpanzee Pan troglodytes XP_521814 848 91186 S807 L D A R S Q A S T S C L P A P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534037 724 78741 R684 L S F L A V G R D V H T F A F
Cat Felis silvestris
Mouse Mus musculus Q9QXJ1 710 77450 S669 L D A R S Q T S T S C L P A P
Rat Rattus norvegicus P46933 711 77638 S670 L D A R S Q T S T S C L P A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507097 616 68316 V576 A R P P S Q K V Q P P P P P P
Chicken Gallus gallus XP_420735 740 81441 Q699 L V A R P P S Q K V R P P P P
Frog Xenopus laevis NP_001087003 610 66956 S570 L D G R P Q G S S C L P T P P
Zebra Danio Brachydanio rerio XP_693392 869 95380 Q827 L V A R P P S Q K A C S Q A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787988 848 93773 L784 L I S S G R F L L R V T N S F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 N.A. 78.3 N.A. 94.6 93.8 N.A. 38.8 45 51.5 39.5 N.A. N.A. N.A. N.A. 31
Protein Similarity: 100 83.7 N.A. 80.6 N.A. 97.1 96 N.A. 53.6 60.9 62.2 53.5 N.A. N.A. N.A. N.A. 47.1
P-Site Identity: 100 100 N.A. 13.3 N.A. 93.3 93.3 N.A. 26.6 33.3 40 33.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 20 N.A. 93.3 93.3 N.A. 26.6 40 46.6 46.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 60 0 10 0 20 0 0 10 0 0 0 60 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 50 0 0 0 0 % C
% Asp: 0 50 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 10 0 0 0 0 0 10 0 20 % F
% Gly: 0 0 10 0 10 0 20 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 20 0 0 0 0 0 0 % K
% Leu: 90 0 0 10 0 0 0 10 10 0 10 40 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 10 10 30 20 0 0 0 10 10 30 60 30 70 % P
% Gln: 0 0 0 0 0 60 0 20 10 0 0 0 10 0 0 % Q
% Arg: 0 10 0 70 0 10 0 10 0 10 10 0 0 0 0 % R
% Ser: 0 10 10 10 50 0 20 50 10 40 0 10 0 10 0 % S
% Thr: 0 0 0 0 0 0 20 0 40 0 0 20 10 0 0 % T
% Val: 0 20 0 0 0 10 0 10 0 20 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _