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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFRSF10A
All Species:
4.55
Human Site:
T461
Identified Species:
14.29
UniProt:
O00220
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00220
NP_003835.2
468
50061
T461
F
I
Y
L
E
D
G
T
G
S
A
V
S
L
E
Chimpanzee
Pan troglodytes
XP_001158464
469
49925
T462
F
I
Y
L
E
D
G
T
G
S
A
V
S
L
E
Rhesus Macaque
Macaca mulatta
XP_001107790
398
43468
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZM4
381
42204
Rat
Rattus norvegicus
Q63199
324
36816
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989446
368
41513
Frog
Xenopus laevis
NP_001084466
328
37234
Zebra Danio
Brachydanio rerio
NP_919372
357
40644
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
70
N.A.
N.A.
33.5
20.2
N.A.
N.A.
25.6
21.3
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
76.7
N.A.
N.A.
49.1
34.6
N.A.
N.A.
39.9
35.2
38.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
N.A.
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
25
% E
% Phe:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
25
0
25
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
25
0
0
0
0
0
0
0
0
0
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
25
0
0
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _