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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKBIE
All Species:
6.67
Human Site:
S173
Identified Species:
14.67
UniProt:
O00221
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00221
NP_004547.2
500
52864
S173
R
S
L
P
E
S
T
S
A
P
A
S
G
P
S
Chimpanzee
Pan troglodytes
XP_518507
500
52781
S173
R
S
L
P
E
S
T
S
A
P
A
S
G
P
S
Rhesus Macaque
Macaca mulatta
XP_001099548
361
38376
E111
A
L
S
P
Q
Q
L
E
A
L
T
Y
I
S
E
Dog
Lupus familis
XP_852039
267
28806
D17
E
T
D
E
S
Q
Y
D
S
G
I
E
S
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O54910
364
39182
E114
V
L
S
P
Q
Q
L
E
A
L
T
Y
I
S
E
Rat
Rattus norvegicus
Q63746
314
34999
E64
Q
E
A
P
L
A
A
E
P
W
K
Q
Q
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514239
326
34667
S76
S
A
A
P
P
L
R
S
A
P
V
P
E
A
Y
Chicken
Gallus gallus
P98150
906
99648
G268
F
Y
E
D
D
E
N
G
W
Q
A
S
G
D
F
Frog
Xenopus laevis
NP_001089595
349
37854
S99
E
E
P
D
I
P
D
S
Q
Q
L
E
C
L
T
Zebra Danio
Brachydanio rerio
NP_001073558
343
38026
N93
Q
Y
T
E
E
E
V
N
F
L
T
T
V
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780345
382
42212
P132
Q
D
E
E
G
D
T
P
L
S
Q
S
I
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
70.5
42.5
N.A.
54.4
26.2
N.A.
36.2
22.1
39.2
31.3
N.A.
N.A.
N.A.
N.A.
25.2
Protein Similarity:
100
99.1
71.4
46.4
N.A.
60.5
38.2
N.A.
43.4
31.4
49.2
45.4
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
100
13.3
0
N.A.
13.3
6.6
N.A.
26.6
20
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
20
13.3
N.A.
20
26.6
N.A.
33.3
26.6
13.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
0
0
10
10
0
46
0
28
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
10
19
10
10
10
10
0
0
0
0
0
10
0
% D
% Glu:
19
19
19
28
28
19
0
28
0
0
0
19
10
0
28
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
10
0
0
10
0
10
0
0
28
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
10
0
28
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
19
19
0
10
10
19
0
10
28
10
0
0
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
55
10
10
0
10
10
28
0
10
0
19
0
% P
% Gln:
28
0
0
0
19
28
0
0
10
19
10
10
10
0
0
% Q
% Arg:
19
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% R
% Ser:
10
19
19
0
10
19
0
37
10
10
0
37
10
19
19
% S
% Thr:
0
10
10
0
0
0
28
0
0
0
28
10
0
10
19
% T
% Val:
10
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
10
0
0
0
0
19
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _