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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKBIE
All Species:
4.24
Human Site:
S216
Identified Species:
9.33
UniProt:
O00221
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00221
NP_004547.2
500
52864
S216
D
S
T
Y
G
S
S
S
L
T
Y
T
L
S
L
Chimpanzee
Pan troglodytes
XP_518507
500
52781
S216
D
S
T
Y
G
S
S
S
L
T
E
T
L
S
L
Rhesus Macaque
Macaca mulatta
XP_001099548
361
38376
V147
L
A
L
L
P
Q
E
V
L
D
I
Q
N
N
L
Dog
Lupus familis
XP_852039
267
28806
P53
P
Q
P
W
T
H
P
P
G
T
A
E
G
P
R
Cat
Felis silvestris
Mouse
Mus musculus
O54910
364
39182
V150
L
A
F
L
P
Q
E
V
L
D
I
Q
N
N
L
Rat
Rattus norvegicus
Q63746
314
34999
D100
V
I
G
Q
V
K
G
D
L
A
F
L
N
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514239
326
34667
A112
P
P
P
P
K
R
T
A
S
P
A
S
R
A
P
Chicken
Gallus gallus
P98150
906
99648
P390
N
N
L
Y
S
S
S
P
H
P
V
G
C
G
Y
Frog
Xenopus laevis
NP_001089595
349
37854
A135
S
L
Y
F
I
S
L
A
P
A
D
V
L
S
I
Zebra Danio
Brachydanio rerio
NP_001073558
343
38026
L129
V
D
L
F
P
P
E
L
M
D
I
Q
N
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780345
382
42212
P168
R
N
C
L
G
Q
T
P
L
M
L
A
V
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
70.5
42.5
N.A.
54.4
26.2
N.A.
36.2
22.1
39.2
31.3
N.A.
N.A.
N.A.
N.A.
25.2
Protein Similarity:
100
99.1
71.4
46.4
N.A.
60.5
38.2
N.A.
43.4
31.4
49.2
45.4
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
93.3
13.3
6.6
N.A.
13.3
6.6
N.A.
0
20
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
26.6
13.3
N.A.
26.6
13.3
N.A.
26.6
33.3
40
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
0
0
19
0
19
19
10
0
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
19
10
0
0
0
0
0
10
0
28
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
28
0
0
0
10
10
0
0
0
% E
% Phe:
0
0
10
19
0
0
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
0
10
0
28
0
10
0
10
0
0
10
10
10
0
% G
% His:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
28
0
0
0
10
% I
% Lys:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
10
28
28
0
0
10
10
55
0
10
10
28
10
46
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
10
19
0
0
0
0
0
0
0
0
0
0
37
28
0
% N
% Pro:
19
10
19
10
28
10
10
28
10
19
0
0
0
10
10
% P
% Gln:
0
10
0
10
0
28
0
0
0
0
0
28
0
0
10
% Q
% Arg:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
10
% R
% Ser:
10
19
0
0
10
37
28
19
10
0
0
10
0
28
0
% S
% Thr:
0
0
19
0
10
0
19
0
0
28
0
19
0
0
10
% T
% Val:
19
0
0
0
10
0
0
19
0
0
10
10
10
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
28
0
0
0
0
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _