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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD12 All Species: 30.61
Human Site: S58 Identified Species: 61.21
UniProt: O00232 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00232 NP_002807.1 456 52904 S58 E K Q T R T A S D M V S T S R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116799 397 46394 Q37 L L S K R R S Q L K Q A V A K
Dog Lupus familis XP_537584 456 52945 S58 E K Q T R T A S D M V S T S R
Cat Felis silvestris
Mouse Mus musculus Q9D8W5 456 52859 S58 E K Q T R T A S D M V S T S R
Rat Rattus norvegicus NP_001005875 456 52918 S58 E K Q T R T A S D M V S T S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510382 521 60536 S123 E K Q T R T A S D M V S T S R
Chicken Gallus gallus NP_001025877 456 52860 S58 E K Q T R T A S D M V S T S R
Frog Xenopus laevis NP_001083999 441 51410 R50 S D M V S T S R I L V A V V K
Zebra Danio Brachydanio rerio NP_963872 456 52795 S58 E K Q T R T A S D M V S T S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649588 502 57729 A58 E K Q T R L G A D M V S C S R
Honey Bee Apis mellifera XP_393370 439 50215 R50 A D V A S T S R I L V A I V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12250 445 51750 S50 E K K T R Q A S D L A S S K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87 99.3 N.A. 96.9 98 N.A. 81.5 93.6 88.5 86.8 N.A. 48.2 57 N.A. N.A.
Protein Similarity: 100 N.A. 87 99.5 N.A. 98.4 99.1 N.A. 83.6 97.5 92.5 93.6 N.A. 65.9 74.1 N.A. N.A.
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 13.3 100 N.A. 73.3 13.3 N.A. N.A.
P-Site Similarity: 100 N.A. 33.3 100 N.A. 100 100 N.A. 100 100 40 100 N.A. 80 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 41.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 65.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 0 67 9 0 0 9 25 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 17 0 0 0 0 0 0 75 0 0 0 0 0 0 % D
% Glu: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 0 9 0 0 % I
% Lys: 0 75 9 9 0 0 0 0 0 9 0 0 0 9 17 % K
% Leu: 9 9 0 0 0 9 0 0 9 25 0 0 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 67 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 67 0 0 9 0 9 0 0 9 0 0 0 9 % Q
% Arg: 0 0 0 0 84 9 0 17 0 0 0 0 0 0 67 % R
% Ser: 9 0 9 0 17 0 25 67 0 0 0 75 9 67 0 % S
% Thr: 0 0 0 75 0 75 0 0 0 0 0 0 59 0 0 % T
% Val: 0 0 9 9 0 0 0 0 0 0 84 0 17 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _