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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD12
All Species:
36.67
Human Site:
T253
Identified Species:
73.33
UniProt:
O00232
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00232
NP_002807.1
456
52904
T253
H
Y
R
A
I
Y
D
T
P
C
I
Q
A
E
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116799
397
46394
E223
I
L
A
P
F
D
N
E
Q
S
D
L
V
H
R
Dog
Lupus familis
XP_537584
456
52945
T253
H
Y
R
A
I
Y
D
T
P
C
I
Q
A
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8W5
456
52859
T253
H
Y
R
A
I
Y
D
T
P
C
I
Q
A
E
S
Rat
Rattus norvegicus
NP_001005875
456
52918
T253
H
Y
R
A
I
Y
D
T
P
C
I
Q
A
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510382
521
60536
T318
H
Y
R
A
I
Y
D
T
P
C
I
Q
A
E
S
Chicken
Gallus gallus
NP_001025877
456
52860
T253
H
Y
R
A
I
Y
D
T
P
C
I
Q
A
E
S
Frog
Xenopus laevis
NP_001083999
441
51410
T238
H
Y
R
A
I
Y
D
T
P
C
I
L
A
E
S
Zebra Danio
Brachydanio rerio
NP_963872
456
52795
T253
H
Y
R
A
I
Y
D
T
P
C
I
L
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649588
502
57729
I300
A
T
E
A
E
V
E
I
E
L
T
E
E
Q
K
Honey Bee
Apis mellifera
XP_393370
439
50215
T241
H
N
R
A
V
L
E
T
P
A
V
R
D
D
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12250
445
51750
T247
Y
L
Q
E
I
Y
Q
T
D
A
I
K
S
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87
99.3
N.A.
96.9
98
N.A.
81.5
93.6
88.5
86.8
N.A.
48.2
57
N.A.
N.A.
Protein Similarity:
100
N.A.
87
99.5
N.A.
98.4
99.1
N.A.
83.6
97.5
92.5
93.6
N.A.
65.9
74.1
N.A.
N.A.
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
100
100
93.3
80
N.A.
6.6
33.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
26.6
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
41.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
65.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
84
0
0
0
0
0
17
0
0
59
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
67
0
9
0
9
0
9
25
0
% D
% Glu:
0
0
9
9
9
0
17
9
9
0
0
9
17
59
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
75
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
75
0
0
9
0
0
75
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% K
% Leu:
0
17
0
0
0
9
0
0
0
9
0
25
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
75
0
0
0
0
0
9
% P
% Gln:
0
0
9
0
0
0
9
0
9
0
0
50
0
9
0
% Q
% Arg:
0
0
75
0
0
0
0
0
0
0
0
9
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
67
% S
% Thr:
0
9
0
0
0
0
0
84
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
9
9
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
67
0
0
0
75
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _