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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGRP
All Species:
4.55
Human Site:
S84
Identified Species:
12.5
UniProt:
O00253
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00253
NP_001129.1
132
14440
S84
Q
D
R
E
P
R
S
S
R
R
C
V
R
L
H
Chimpanzee
Pan troglodytes
NP_001129099
132
14575
A83
E
A
S
M
K
K
V
A
R
P
R
T
P
L
S
Rhesus Macaque
Macaca mulatta
XP_001091740
132
14382
S84
Q
D
R
E
P
R
S
S
R
R
C
V
R
L
H
Dog
Lupus familis
XP_853932
132
14378
P84
E
G
R
E
P
R
S
P
R
R
C
V
R
L
H
Cat
Felis silvestris
Mouse
Mus musculus
P56473
131
14413
P83
Q
N
R
E
S
R
S
P
R
R
C
V
R
L
H
Rat
Rattus norvegicus
Q99JA2
131
14257
I80
S
S
K
K
K
A
S
I
K
K
V
A
R
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506592
140
15644
P93
Q
G
R
E
E
R
S
P
R
R
C
V
R
L
L
Chicken
Gallus gallus
NP_001026628
165
17886
P118
G
R
E
E
R
S
S
P
R
R
C
V
R
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001092125
135
15159
L88
Q
G
R
A
M
R
S
L
R
R
C
I
P
H
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.5
95.4
81.8
N.A.
80.3
21.2
N.A.
50.7
44.2
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
48.4
97.7
89.3
N.A.
87.1
43.1
N.A.
59.2
52.1
N.A.
N.A.
51.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
80
N.A.
80
13.3
N.A.
73.3
53.3
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
86.6
N.A.
86.6
40
N.A.
73.3
53.3
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
0
12
0
12
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% C
% Asp:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
23
0
12
67
12
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
45
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% I
% Lys:
0
0
12
12
23
12
0
0
12
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
0
0
0
78
23
% L
% Met:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
34
0
0
45
0
12
0
0
23
12
12
% P
% Gln:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
12
67
0
12
67
0
0
89
78
12
0
78
0
0
% R
% Ser:
12
12
12
0
12
12
89
23
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
12
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _