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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGRP All Species: 4.55
Human Site: S84 Identified Species: 12.5
UniProt: O00253 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00253 NP_001129.1 132 14440 S84 Q D R E P R S S R R C V R L H
Chimpanzee Pan troglodytes NP_001129099 132 14575 A83 E A S M K K V A R P R T P L S
Rhesus Macaque Macaca mulatta XP_001091740 132 14382 S84 Q D R E P R S S R R C V R L H
Dog Lupus familis XP_853932 132 14378 P84 E G R E P R S P R R C V R L H
Cat Felis silvestris
Mouse Mus musculus P56473 131 14413 P83 Q N R E S R S P R R C V R L H
Rat Rattus norvegicus Q99JA2 131 14257 I80 S S K K K A S I K K V A R P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506592 140 15644 P93 Q G R E E R S P R R C V R L L
Chicken Gallus gallus NP_001026628 165 17886 P118 G R E E R S S P R R C V R L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001092125 135 15159 L88 Q G R A M R S L R R C I P H Q
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.5 95.4 81.8 N.A. 80.3 21.2 N.A. 50.7 44.2 N.A. N.A. 40 N.A. N.A. N.A. N.A.
Protein Similarity: 100 48.4 97.7 89.3 N.A. 87.1 43.1 N.A. 59.2 52.1 N.A. N.A. 51.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 80 N.A. 80 13.3 N.A. 73.3 53.3 N.A. N.A. 46.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 86.6 N.A. 86.6 40 N.A. 73.3 53.3 N.A. N.A. 53.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 12 0 12 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 78 0 0 0 0 % C
% Asp: 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 23 0 12 67 12 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 45 % H
% Ile: 0 0 0 0 0 0 0 12 0 0 0 12 0 0 0 % I
% Lys: 0 0 12 12 23 12 0 0 12 12 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 12 0 0 0 0 0 78 23 % L
% Met: 0 0 0 12 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 34 0 0 45 0 12 0 0 23 12 12 % P
% Gln: 56 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Q
% Arg: 0 12 67 0 12 67 0 0 89 78 12 0 78 0 0 % R
% Ser: 12 12 12 0 12 12 89 23 0 0 0 0 0 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % T
% Val: 0 0 0 0 0 0 12 0 0 0 12 67 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _