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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F2RL2 All Species: 4.85
Human Site: S47 Identified Species: 11.85
UniProt: O00254 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00254 NP_004092.1 374 42508 S47 F R G A P P N S F E E F P F S
Chimpanzee Pan troglodytes XP_001145175 397 44163 G52 T S H V T G K G V T V E T V F
Rhesus Macaque Macaca mulatta XP_001106069 374 42547 S47 F R G A P P D S F E E F P F S
Dog Lupus familis XP_849866 379 43321 F48 R G A P S N S F E E F P L S A
Cat Felis silvestris
Mouse Mus musculus O08675 369 41689 K37 A K P T L T I K S F N G G P Q
Rat Rattus norvegicus Q920E1 368 41777 E37 D N S A L T A E S F N G N E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513801 393 43481 N46 G R S L I G H N T L N G T C V
Chicken Gallus gallus XP_001231246 378 43407 Y46 I S P R D Y D Y I P P H A I E
Frog Xenopus laevis P47749 420 47417 F54 F D D S E S E F E E I P W D E
Zebra Danio Brachydanio rerio XP_001344158 372 41784 G37 R N S T G S V G P R T F K G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.4 98.4 86.8 N.A. 69.7 69.7 N.A. 34.8 60.5 31.4 38.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 50.8 99.1 90.7 N.A. 81.8 79.4 N.A. 52.6 72.2 49.7 54.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 6.6 N.A. 0 6.6 N.A. 6.6 0 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 20 N.A. 6.6 6.6 N.A. 20 6.6 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 30 0 0 10 0 0 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 10 10 0 10 0 20 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 0 10 10 20 40 20 10 0 10 20 % E
% Phe: 30 0 0 0 0 0 0 20 20 20 10 30 0 20 10 % F
% Gly: 10 10 20 0 10 20 0 20 0 0 0 30 10 10 0 % G
% His: 0 0 10 0 0 0 10 0 0 0 0 10 0 0 10 % H
% Ile: 10 0 0 0 10 0 10 0 10 0 10 0 0 10 0 % I
% Lys: 0 10 0 0 0 0 10 10 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 10 20 0 0 0 0 10 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 0 10 10 10 0 0 30 0 10 0 0 % N
% Pro: 0 0 20 10 20 20 0 0 10 10 10 20 20 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 20 30 0 10 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 20 30 10 10 20 10 20 20 0 0 0 0 10 30 % S
% Thr: 10 0 0 20 10 20 0 0 10 10 10 0 20 0 0 % T
% Val: 0 0 0 10 0 0 10 0 10 0 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _