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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F2RL2
All Species:
10.61
Human Site:
S76
Identified Species:
25.93
UniProt:
O00254
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00254
NP_004092.1
374
42508
S76
K
C
P
E
E
S
A
S
H
L
H
V
K
N
A
Chimpanzee
Pan troglodytes
XP_001145175
397
44163
V81
T
T
V
F
L
P
I
V
Y
T
I
V
F
V
V
Rhesus Macaque
Macaca mulatta
XP_001106069
374
42547
S76
K
C
P
E
E
S
A
S
H
L
H
V
K
N
A
Dog
Lupus familis
XP_849866
379
43321
S77
K
C
P
E
E
S
V
S
N
L
Q
V
N
N
A
Cat
Felis silvestris
Mouse
Mus musculus
O08675
369
41689
K66
T
G
A
T
T
T
I
K
A
E
C
P
E
D
S
Rat
Rattus norvegicus
Q920E1
368
41777
A66
G
A
T
T
T
I
K
A
K
C
P
E
E
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513801
393
43481
T75
V
F
L
P
I
V
Y
T
I
V
F
I
I
G
I
Chicken
Gallus gallus
XP_001231246
378
43407
T75
L
K
K
Y
N
D
S
T
L
I
E
V
N
N
T
Frog
Xenopus laevis
P47749
420
47417
I83
S
R
S
A
R
K
P
I
R
R
N
I
T
K
E
Zebra Danio
Brachydanio rerio
XP_001344158
372
41784
A66
Q
T
P
P
P
S
N
A
V
V
L
N
S
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.4
98.4
86.8
N.A.
69.7
69.7
N.A.
34.8
60.5
31.4
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.8
99.1
90.7
N.A.
81.8
79.4
N.A.
52.6
72.2
49.7
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
0
0
N.A.
0
13.3
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
80
N.A.
26.6
20
N.A.
20
33.3
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
20
20
10
0
0
0
0
0
30
% A
% Cys:
0
30
0
0
0
0
0
0
0
10
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
30
30
0
0
0
0
10
10
10
20
0
10
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
10
0
10
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
20
0
20
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
20
10
10
10
10
20
10
0
20
% I
% Lys:
30
10
10
0
0
10
10
10
10
0
0
0
20
10
0
% K
% Leu:
10
0
10
0
10
0
0
0
10
30
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
10
0
10
10
20
50
10
% N
% Pro:
0
0
40
20
10
10
10
0
0
0
10
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
10
0
10
0
0
40
10
30
0
0
0
0
10
10
10
% S
% Thr:
20
20
10
20
20
10
0
20
0
10
0
0
10
0
10
% T
% Val:
10
0
10
0
0
10
10
10
10
20
0
50
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _