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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEN1
All Species:
18.48
Human Site:
S464
Identified Species:
40.67
UniProt:
O00255
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00255
NP_000235.2
615
67993
S464
R
Q
K
V
R
I
V
S
R
E
A
E
A
A
E
Chimpanzee
Pan troglodytes
XP_001166862
615
67973
S464
R
Q
K
V
R
I
V
S
R
E
A
E
A
A
E
Rhesus Macaque
Macaca mulatta
XP_001118239
293
32543
Y161
W
L
Y
L
K
G
S
Y
M
R
C
D
R
K
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88559
611
67454
S459
R
Q
K
V
H
M
V
S
R
E
A
E
A
A
G
Rat
Rattus norvegicus
NP_062081
610
67317
S459
R
Q
K
V
H
I
V
S
R
E
A
E
A
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514516
282
29931
A149
I
V
S
R
E
A
E
A
T
E
T
E
E
P
W
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121241
675
74671
C527
L
R
F
Y
D
G
I
C
K
W
E
E
D
S
P
Zebra Danio
Brachydanio rerio
NP_571028
617
68750
T458
R
Q
K
V
S
I
I
T
K
D
T
E
P
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523498
763
82846
E482
K
A
E
L
A
R
A
E
Q
E
A
K
E
A
K
Honey Bee
Apis mellifera
XP_394464
606
67605
S445
K
S
Q
K
R
E
T
S
P
E
E
T
L
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794534
680
76850
D530
A
G
T
G
L
L
W
D
T
K
T
E
F
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
44.7
N.A.
N.A.
95.4
96.2
N.A.
36.7
N.A.
59.2
66.7
N.A.
32.9
42.5
N.A.
42.5
Protein Similarity:
100
99.8
45.5
N.A.
N.A.
96.4
97
N.A.
40.3
N.A.
70
78.7
N.A.
47.8
57
N.A.
60
P-Site Identity:
100
100
0
N.A.
N.A.
80
93.3
N.A.
13.3
N.A.
6.6
40
N.A.
20
20
N.A.
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
86.6
93.3
N.A.
20
N.A.
33.3
73.3
N.A.
60
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
10
10
10
0
0
46
0
37
46
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
10
0
10
10
0
19
% D
% Glu:
0
0
10
0
10
10
10
10
0
64
19
73
19
0
28
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
10
0
19
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
37
19
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
46
10
10
0
0
0
19
10
0
10
0
10
10
% K
% Leu:
10
10
0
19
10
10
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
10
% P
% Gln:
0
46
10
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
46
10
0
10
28
10
0
0
37
10
0
0
10
0
0
% R
% Ser:
0
10
10
0
10
0
10
46
0
0
0
0
0
19
0
% S
% Thr:
0
0
10
0
0
0
10
10
19
0
28
10
0
0
0
% T
% Val:
0
10
0
46
0
0
37
0
0
0
0
0
0
10
0
% V
% Trp:
10
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% W
% Tyr:
0
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _