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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEN1
All Species:
13.64
Human Site:
S548
Identified Species:
30
UniProt:
O00255
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00255
NP_000235.2
615
67993
S548
Q
V
P
A
P
A
A
S
P
P
P
E
G
P
V
Chimpanzee
Pan troglodytes
XP_001166862
615
67973
S548
Q
V
P
A
P
A
A
S
P
P
P
E
G
P
V
Rhesus Macaque
Macaca mulatta
XP_001118239
293
32543
G228
E
E
L
E
P
T
P
G
R
P
D
P
L
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88559
611
67454
S544
Q
A
P
A
P
A
A
S
P
P
P
E
G
P
V
Rat
Rattus norvegicus
NP_062081
610
67317
S543
Q
A
P
A
P
A
A
S
P
P
P
E
G
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514516
282
29931
P217
P
A
P
P
A
S
P
P
P
E
G
P
V
L
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121241
675
74671
S608
P
P
Q
K
G
E
E
S
E
Y
E
Q
L
L
T
Zebra Danio
Brachydanio rerio
NP_571028
617
68750
P550
I
P
S
P
S
Q
P
P
A
V
Q
G
G
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523498
763
82846
E651
S
D
D
Y
D
P
F
E
I
M
L
K
R
P
V
Honey Bee
Apis mellifera
XP_394464
606
67605
D540
L
D
P
E
D
E
T
D
S
E
H
E
R
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794534
680
76850
P613
L
E
D
S
I
N
L
P
P
Q
P
V
P
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
44.7
N.A.
N.A.
95.4
96.2
N.A.
36.7
N.A.
59.2
66.7
N.A.
32.9
42.5
N.A.
42.5
Protein Similarity:
100
99.8
45.5
N.A.
N.A.
96.4
97
N.A.
40.3
N.A.
70
78.7
N.A.
47.8
57
N.A.
60
P-Site Identity:
100
100
13.3
N.A.
N.A.
93.3
93.3
N.A.
13.3
N.A.
6.6
20
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
100
26.6
N.A.
N.A.
93.3
93.3
N.A.
20
N.A.
13.3
20
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
0
37
10
37
37
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
19
0
19
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
10
19
0
19
0
19
10
10
10
19
10
46
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
0
10
10
46
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
19
0
10
0
0
0
10
0
0
0
10
0
19
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
19
55
19
46
10
28
28
55
46
46
19
10
64
0
% P
% Gln:
37
0
10
0
0
10
0
0
0
10
10
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
19
0
10
% R
% Ser:
10
0
10
10
10
10
0
46
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
10
0
0
0
0
0
0
10
19
% T
% Val:
0
19
0
0
0
0
0
0
0
10
0
10
10
0
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _