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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEN1
All Species:
32.73
Human Site:
S588
Identified Species:
72
UniProt:
O00255
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00255
NP_000235.2
615
67993
S588
K
L
Q
L
T
A
Q
S
Q
V
Q
M
K
K
Q
Chimpanzee
Pan troglodytes
XP_001166862
615
67973
S588
K
L
Q
L
T
A
Q
S
Q
V
Q
M
K
K
Q
Rhesus Macaque
Macaca mulatta
XP_001118239
293
32543
P268
R
P
N
P
V
P
G
P
A
A
P
G
P
P
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88559
611
67454
S584
K
L
Q
L
T
A
Q
S
Q
V
Q
M
K
K
Q
Rat
Rattus norvegicus
NP_062081
610
67317
S583
K
L
Q
L
T
A
Q
S
Q
V
Q
M
K
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514516
282
29931
V257
Q
L
T
A
Q
S
Q
V
Q
M
K
K
Q
K
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121241
675
74671
S648
K
L
Q
L
T
A
Q
S
Q
V
Q
P
K
R
A
Zebra Danio
Brachydanio rerio
NP_571028
617
68750
S590
K
L
Q
L
T
A
Q
S
Q
V
Q
M
K
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523498
763
82846
S691
S
L
Q
V
T
A
Q
S
V
A
S
R
K
V
R
Honey Bee
Apis mellifera
XP_394464
606
67605
S580
S
L
Q
L
T
A
Q
S
Q
V
Q
I
G
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794534
680
76850
S653
H
L
Q
L
T
A
Q
S
Q
V
Q
V
G
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
44.7
N.A.
N.A.
95.4
96.2
N.A.
36.7
N.A.
59.2
66.7
N.A.
32.9
42.5
N.A.
42.5
Protein Similarity:
100
99.8
45.5
N.A.
N.A.
96.4
97
N.A.
40.3
N.A.
70
78.7
N.A.
47.8
57
N.A.
60
P-Site Identity:
100
100
0
N.A.
N.A.
100
100
N.A.
26.6
N.A.
80
93.3
N.A.
46.6
73.3
N.A.
73.3
P-Site Similarity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
60
N.A.
86.6
100
N.A.
60
86.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
82
0
0
10
19
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
10
19
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
55
0
0
0
0
0
0
0
0
0
10
10
64
64
10
% K
% Leu:
0
91
0
73
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
46
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
10
0
10
0
10
0
0
10
10
10
10
10
% P
% Gln:
10
0
82
0
10
0
91
0
82
0
73
0
10
0
46
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
10
0
19
19
% R
% Ser:
19
0
0
0
0
10
0
82
0
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
82
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
10
10
73
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _