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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEN1 All Species: 16.97
Human Site: S601 Identified Species: 37.33
UniProt: O00255 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00255 NP_000235.2 615 67993 S601 K Q K V S T P S D Y T L S F L
Chimpanzee Pan troglodytes XP_001166862 615 67973 S601 K Q K V S T P S D Y T L S F L
Rhesus Macaque Macaca mulatta XP_001118239 293 32543 S281 P P R R P F S S L F V R L A P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88559 611 67454 S597 K Q K V S T P S D Y T L S F L
Rat Rattus norvegicus NP_062081 610 67317 S596 K Q K V S T P S D Y T L S F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514516 282 29931 Y270 K V S A P S D Y T L S F L K R
Chicken Gallus gallus
Frog Xenopus laevis NP_001121241 675 74671 R661 R A R G S G A R D Y N L G Y L
Zebra Danio Brachydanio rerio NP_571028 617 68750 G603 R Q K P T A S G D Y T L S F M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523498 763 82846 S704 V R G V E K H S A T I S A T I
Honey Bee Apis mellifera XP_394464 606 67605 E593 K K S R G T D E V G V S Q R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794534 680 76850 D666 K R I R S T N D Y E D Y G T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 44.7 N.A. N.A. 95.4 96.2 N.A. 36.7 N.A. 59.2 66.7 N.A. 32.9 42.5 N.A. 42.5
Protein Similarity: 100 99.8 45.5 N.A. N.A. 96.4 97 N.A. 40.3 N.A. 70 78.7 N.A. 47.8 57 N.A. 60
P-Site Identity: 100 100 6.6 N.A. N.A. 100 100 N.A. 6.6 N.A. 33.3 53.3 N.A. 13.3 13.3 N.A. 26.6
P-Site Similarity: 100 100 20 N.A. N.A. 100 100 N.A. 20 N.A. 53.3 73.3 N.A. 33.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 10 10 0 10 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 19 10 55 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 10 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 10 0 10 0 46 0 % F
% Gly: 0 0 10 10 10 10 0 10 0 10 0 0 19 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 10 % I
% Lys: 64 10 46 0 0 10 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 10 0 55 19 0 55 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % N
% Pro: 10 10 0 10 19 0 37 0 0 0 0 0 0 0 19 % P
% Gln: 0 46 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 19 19 19 28 0 0 0 10 0 0 0 10 0 10 10 % R
% Ser: 0 0 19 0 55 10 19 55 0 0 10 19 46 0 0 % S
% Thr: 0 0 0 0 10 55 0 0 10 10 46 0 0 19 0 % T
% Val: 10 10 0 46 0 0 0 0 10 0 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 10 55 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _