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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEN1
All Species:
17.88
Human Site:
T443
Identified Species:
39.33
UniProt:
O00255
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00255
NP_000235.2
615
67993
T443
V
L
H
V
G
W
A
T
F
L
V
Q
S
L
G
Chimpanzee
Pan troglodytes
XP_001166862
615
67973
T443
V
L
H
V
G
W
A
T
F
L
V
Q
S
L
G
Rhesus Macaque
Macaca mulatta
XP_001118239
293
32543
Q141
F
K
D
R
A
H
I
Q
S
L
F
S
F
I
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88559
611
67454
T438
V
L
H
V
G
W
A
T
F
L
V
Q
S
L
G
Rat
Rattus norvegicus
NP_062081
610
67317
T438
V
L
H
V
G
W
A
T
F
L
V
Q
S
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514516
282
29931
G129
M
C
S
D
P
S
P
G
S
S
P
E
L
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121241
675
74671
E498
L
P
N
L
L
K
E
E
A
M
S
P
D
G
P
Zebra Danio
Brachydanio rerio
NP_571028
617
68750
T437
V
L
H
V
G
W
A
T
Y
L
V
Q
S
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523498
763
82846
Q460
F
D
Y
D
I
R
S
Q
V
V
I
K
L
P
E
Honey Bee
Apis mellifera
XP_394464
606
67605
Q422
F
D
A
S
I
R
A
Q
V
I
I
E
C
Y
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794534
680
76850
G500
A
D
G
C
G
K
K
G
K
A
E
N
E
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
44.7
N.A.
N.A.
95.4
96.2
N.A.
36.7
N.A.
59.2
66.7
N.A.
32.9
42.5
N.A.
42.5
Protein Similarity:
100
99.8
45.5
N.A.
N.A.
96.4
97
N.A.
40.3
N.A.
70
78.7
N.A.
47.8
57
N.A.
60
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
0
N.A.
0
86.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
13.3
N.A.
26.6
93.3
N.A.
33.3
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
0
55
0
10
10
0
0
0
10
0
% A
% Cys:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
28
10
19
0
0
0
0
0
0
0
0
10
0
10
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
10
19
10
0
19
% E
% Phe:
28
0
0
0
0
0
0
0
37
0
10
0
10
0
0
% F
% Gly:
0
0
10
0
55
0
0
19
0
0
0
0
0
19
37
% G
% His:
0
0
46
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
19
0
10
0
0
10
19
0
0
10
0
% I
% Lys:
0
10
0
0
0
19
10
0
10
0
0
10
0
0
0
% K
% Leu:
10
46
0
10
10
0
0
0
0
55
0
0
19
46
0
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
10
0
0
10
0
10
0
0
0
10
10
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
28
0
0
0
46
0
0
0
% Q
% Arg:
0
0
0
10
0
19
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
0
10
10
0
19
10
10
10
46
0
10
% S
% Thr:
0
0
0
0
0
0
0
46
0
0
0
0
0
0
10
% T
% Val:
46
0
0
46
0
0
0
0
19
10
46
0
0
0
10
% V
% Trp:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _