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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEN1 All Species: 5.15
Human Site: T539 Identified Species: 11.33
UniProt: O00255 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00255 NP_000235.2 615 67993 T539 R G P E G G S T A Q V P A P A
Chimpanzee Pan troglodytes XP_001166862 615 67973 T539 R G P E G G S T A Q V P A P A
Rhesus Macaque Macaca mulatta XP_001118239 293 32543 D219 M A L G N L A D L E E L E P T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88559 611 67454 A535 G G Q E V G N A A Q A P A P A
Rat Rattus norvegicus NP_062081 610 67317 A534 R G T E V S S A A Q A P A P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514516 282 29931 P208 R G P E G P A P P P A P P A S
Chicken Gallus gallus
Frog Xenopus laevis NP_001121241 675 74671 N599 S T Q L S S H N G P P Q K G E
Zebra Danio Brachydanio rerio NP_571028 617 68750 S541 K N E P S S P S P I P S P S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523498 763 82846 E642 H K E A K K E E T S D D Y D P
Honey Bee Apis mellifera XP_394464 606 67605 E531 P A P S T S Q E N L D P E D E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794534 680 76850 D604 D E D D E T K D E L E D S I N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 44.7 N.A. N.A. 95.4 96.2 N.A. 36.7 N.A. 59.2 66.7 N.A. 32.9 42.5 N.A. 42.5
Protein Similarity: 100 99.8 45.5 N.A. N.A. 96.4 97 N.A. 40.3 N.A. 70 78.7 N.A. 47.8 57 N.A. 60
P-Site Identity: 100 100 6.6 N.A. N.A. 60 66.6 N.A. 40 N.A. 0 0 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 100 20 N.A. N.A. 66.6 66.6 N.A. 53.3 N.A. 0 13.3 N.A. 0 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 10 0 0 19 19 37 0 28 0 37 10 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 10 0 0 0 19 0 0 19 19 0 19 0 % D
% Glu: 0 10 19 46 10 0 10 19 10 10 19 0 19 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 46 0 10 28 28 0 0 10 0 0 0 0 10 0 % G
% His: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % I
% Lys: 10 10 0 0 10 10 10 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 10 10 0 10 0 0 10 19 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 0 10 10 10 0 0 0 0 0 10 % N
% Pro: 10 0 37 10 0 10 10 10 19 19 19 55 19 46 10 % P
% Gln: 0 0 19 0 0 0 10 0 0 37 0 10 0 0 10 % Q
% Arg: 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 10 19 37 28 10 0 10 0 10 10 10 10 % S
% Thr: 0 10 10 0 10 10 0 19 10 0 0 0 0 0 10 % T
% Val: 0 0 0 0 19 0 0 0 0 0 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _