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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBX4 All Species: 9.7
Human Site: S192 Identified Species: 26.67
UniProt: O00257 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00257 NP_003646.2 560 61368 S192 C P D L G A K S H P P D K W A
Chimpanzee Pan troglodytes XP_523736 378 42282 F57 D A R L L A A F E E R E R E M
Rhesus Macaque Macaca mulatta XP_001109437 837 88730 P262 V Q E L Q G P P T P T P R S S
Dog Lupus familis XP_850702 632 67994 S271 C P D L G A K S H P P D K W A
Cat Felis silvestris
Mouse Mus musculus O55187 551 60504 S192 C P D L G T K S H P P D K W A
Rat Rattus norvegicus P60889 158 17948
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989973 523 58166 L192 L D S T K S P L G A H P D K W
Frog Xenopus laevis NP_001080949 521 58786 T190 N R H R D S L T H T Q A A D M
Zebra Danio Brachydanio rerio NP_991312 477 54249 N156 K K H F Y Q L N S K K H H H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.1 58.2 78.4 N.A. 89.6 20.7 N.A. N.A. 62.1 49.4 42.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 36.9 59.5 80.6 N.A. 91.9 24.8 N.A. N.A. 68.7 60.8 55.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 13.3 100 N.A. 93.3 0 N.A. N.A. 0 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 33.3 100 N.A. 93.3 0 N.A. N.A. 6.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 34 12 0 0 12 0 12 12 0 34 % A
% Cys: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 12 34 0 12 0 0 0 0 0 0 34 12 12 0 % D
% Glu: 0 0 12 0 0 0 0 0 12 12 0 12 0 12 0 % E
% Phe: 0 0 0 12 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 34 12 0 0 12 0 0 0 0 0 0 % G
% His: 0 0 23 0 0 0 0 0 45 0 12 12 12 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 12 0 0 12 0 34 0 0 12 12 0 34 12 0 % K
% Leu: 12 0 0 56 12 0 23 12 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % M
% Asn: 12 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 34 0 0 0 0 23 12 0 45 34 23 0 0 0 % P
% Gln: 0 12 0 0 12 12 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 12 12 12 0 0 0 0 0 0 12 0 23 0 0 % R
% Ser: 0 0 12 0 0 23 0 34 12 0 0 0 0 12 12 % S
% Thr: 0 0 0 12 0 12 0 12 12 12 12 0 0 0 0 % T
% Val: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 12 % W
% Tyr: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _