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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRB
All Species:
22.42
Human Site:
S47
Identified Species:
61.67
UniProt:
O00258
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00258
NP_004618.2
174
19780
S47
Q
K
D
A
E
Q
E
S
Q
M
R
A
E
I
Q
Chimpanzee
Pan troglodytes
XP_514900
402
44614
S175
Q
K
D
A
E
Q
E
S
Q
M
R
A
E
I
Q
Rhesus Macaque
Macaca mulatta
XP_001092285
91
10657
Dog
Lupus familis
XP_849833
174
19806
A47
Q
K
D
A
E
Q
E
A
Q
M
R
A
E
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0D7
174
19848
S47
Q
K
D
A
E
Q
E
S
Q
M
R
A
E
I
Q
Rat
Rattus norvegicus
Q6P6S5
174
19880
S47
Q
K
D
A
E
Q
E
S
Q
M
R
A
E
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510802
251
28010
S124
Q
K
D
A
E
Q
E
S
Q
M
R
M
E
I
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089417
170
19395
S47
E
Q
E
Y
Q
M
R
S
D
I
Q
Y
M
R
Q
Zebra Danio
Brachydanio rerio
Q6DRM0
170
19200
T47
D
Q
E
M
E
M
R
T
E
I
Q
N
M
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.3
41.3
95.9
N.A.
93
91.9
N.A.
57.3
N.A.
74.7
68.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.5
45.9
98.2
N.A.
96.5
95.9
N.A.
64.1
N.A.
87.9
84.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
93.3
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
93.3
N.A.
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
0
0
12
0
0
0
56
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
67
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
12
0
23
0
78
0
67
0
12
0
0
0
67
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
23
0
0
0
67
0
% I
% Lys:
0
67
0
0
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
0
23
0
0
0
67
0
12
23
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
67
23
0
0
12
67
0
0
67
0
23
0
0
0
78
% Q
% Arg:
0
0
0
0
0
0
23
0
0
0
67
0
0
12
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _