KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGRMC1
All Species:
21.21
Human Site:
T101
Identified Species:
38.89
UniProt:
O00264
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00264
NP_006658.1
195
21671
T101
N
G
K
V
F
D
V
T
K
G
R
K
F
Y
G
Chimpanzee
Pan troglodytes
XP_001135589
188
20668
N94
P
R
I
L
M
A
I
N
G
K
V
F
D
V
T
Rhesus Macaque
Macaca mulatta
XP_001100639
204
22721
E110
G
R
K
F
Y
G
P
E
L
I
F
G
F
V
F
Dog
Lupus familis
XP_538151
195
21592
T101
N
G
K
V
F
D
V
T
K
G
R
K
F
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
O55022
195
21676
T101
N
G
K
V
F
D
V
T
K
G
R
K
F
Y
G
Rat
Rattus norvegicus
P70580
195
21580
T101
N
G
K
V
F
D
V
T
K
G
R
K
F
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKN2
192
21263
T99
N
G
K
V
F
D
V
T
R
A
S
K
F
Y
G
Frog
Xenopus laevis
NP_001085424
177
20185
G84
K
V
F
D
V
T
R
G
K
K
F
Y
G
P
D
Zebra Danio
Brachydanio rerio
NP_001007393
179
20264
D86
A
V
N
G
K
V
F
D
V
T
R
G
K
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573087
248
27902
V111
V
N
G
S
V
Y
D
V
S
K
G
R
R
F
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783332
173
19917
F80
V
A
V
N
G
K
V
F
D
V
S
R
G
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2Z4
233
25364
S100
K
G
Q
I
Y
D
V
S
Q
S
R
M
F
Y
G
Baker's Yeast
Sacchar. cerevisiae
Q12091
152
16739
K59
F
N
G
H
D
D
E
K
I
F
I
A
I
R
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.5
94.6
94.8
N.A.
95.3
93.3
N.A.
N.A.
71.2
65.6
65.1
N.A.
42.3
N.A.
N.A.
53.8
Protein Similarity:
100
85.1
95
97.4
N.A.
98.4
97.4
N.A.
N.A.
82
80.5
81.5
N.A.
54.8
N.A.
N.A.
71.2
P-Site Identity:
100
0
13.3
100
N.A.
100
100
N.A.
N.A.
80
6.6
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
20
100
N.A.
100
100
N.A.
N.A.
86.6
6.6
6.6
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.3
32.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
54
8
8
8
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
8
8
39
0
8
8
0
8
16
8
54
8
16
% F
% Gly:
8
47
16
8
8
8
0
8
8
31
8
16
16
0
54
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
8
0
8
8
8
0
8
0
0
% I
% Lys:
16
0
47
0
8
8
0
8
39
24
0
39
8
8
8
% K
% Leu:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
39
16
8
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
16
0
0
0
0
8
0
8
0
47
16
8
16
0
% R
% Ser:
0
0
0
8
0
0
0
8
8
8
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
39
0
8
0
0
0
0
8
% T
% Val:
16
16
8
39
16
8
54
8
8
8
8
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
8
0
0
0
0
0
8
0
47
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _