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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT5H All Species: 31.52
Human Site: S818 Identified Species: 57.78
UniProt: O00267 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00267 NP_001104490.1 1087 121000 S818 G S R T P A Q S G A W D P N N
Chimpanzee Pan troglodytes XP_512652 1144 127380 S875 G S R T P A Q S G A W D P N N
Rhesus Macaque Macaca mulatta XP_001088495 1087 121009 S818 G S R T P A Q S G A W D P N N
Dog Lupus familis XP_533673 1087 121018 S818 G S R T P A Q S G A W D P N N
Cat Felis silvestris
Mouse Mus musculus O55201 1082 120646 S812 G S R T P A Q S G A W D P N N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513022 882 99015 C637 E N G G M F V C K T R H L V L
Chicken Gallus gallus Q5ZI08 1079 119963 S810 G S R T P A Q S G A W D P N N
Frog Xenopus laevis NP_001089092 1083 120609 S815 G S R T P A Q S G A W D P N N
Zebra Danio Brachydanio rerio Q9DDT5 1084 120360 S816 G S R T P G Q S G A W D P N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V460 1078 119426 G829 G S K T P L V G S Q T P N W D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21338 1208 133339 G844 T P A Y G E G G R T P A Y G S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9STN3 1054 117124 P806 P L H P Y M T P M R D S G A T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S3C4 1052 114099 V791 T T D T H A R V E L H S R G K
Conservation
Percent
Protein Identity: 100 94.2 99.8 99.6 N.A. 97.4 N.A. N.A. 78.4 94.9 90.3 88 N.A. 55.9 N.A. 39.6 N.A.
Protein Similarity: 100 94.3 100 99.8 N.A. 98.8 N.A. N.A. 79.6 96.5 95.4 93 N.A. 72.1 N.A. 57 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 0 100 100 93.3 N.A. 26.6 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 100 100 93.3 N.A. 40 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 33.2 N.A. 30.9
Protein Similarity: N.A. N.A. N.A. 52.4 N.A. 47.9
P-Site Identity: N.A. N.A. N.A. 0 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 0 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 62 0 0 0 62 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 8 62 0 0 8 % D
% Glu: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 70 0 8 8 8 8 8 16 62 0 0 0 8 16 0 % G
% His: 0 0 8 0 8 0 0 0 0 0 8 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 8 % K
% Leu: 0 8 0 0 0 8 0 0 0 8 0 0 8 0 8 % L
% Met: 0 0 0 0 8 8 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 8 62 62 % N
% Pro: 8 8 0 8 70 0 0 8 0 0 8 8 62 0 0 % P
% Gln: 0 0 0 0 0 0 62 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 62 0 0 0 8 0 8 8 8 0 8 0 0 % R
% Ser: 0 70 0 0 0 0 0 62 8 0 0 16 0 0 8 % S
% Thr: 16 8 0 77 0 0 8 0 0 16 8 0 0 0 8 % T
% Val: 0 0 0 0 0 0 16 8 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 62 0 0 8 0 % W
% Tyr: 0 0 0 8 8 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _