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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUPT5H
All Species:
36.06
Human Site:
Y224
Identified Species:
66.11
UniProt:
O00267
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00267
NP_001104490.1
1087
121000
Y224
A
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Chimpanzee
Pan troglodytes
XP_512652
1144
127380
Y281
A
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Rhesus Macaque
Macaca mulatta
XP_001088495
1087
121009
Y224
A
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Dog
Lupus familis
XP_533673
1087
121018
Y224
A
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
O55201
1082
120646
Y222
A
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513022
882
99015
I98
W
E
D
G
A
E
D
I
L
E
K
E
E
I
E
Chicken
Gallus gallus
Q5ZI08
1079
119963
Y221
A
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Frog
Xenopus laevis
NP_001089092
1083
120609
Y225
S
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Zebra Danio
Brachydanio rerio
Q9DDT5
1084
120360
Y223
A
P
E
H
V
K
G
Y
I
Y
V
E
A
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V460
1078
119426
Y261
A
P
E
G
V
K
G
Y
I
Y
L
E
A
Y
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21338
1208
133339
M230
V
K
E
G
L
K
G
M
I
Y
I
E
A
F
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STN3
1054
117124
F226
A
L
D
H
L
K
N
F
I
Y
V
E
A
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3C4
1052
114099
R217
Y
G
K
R
A
P
A
R
G
Y
G
D
M
A
I
Conservation
Percent
Protein Identity:
100
94.2
99.8
99.6
N.A.
97.4
N.A.
N.A.
78.4
94.9
90.3
88
N.A.
55.9
N.A.
39.6
N.A.
Protein Similarity:
100
94.3
100
99.8
N.A.
98.8
N.A.
N.A.
79.6
96.5
95.4
93
N.A.
72.1
N.A.
57
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
100
93.3
100
N.A.
86.6
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
33.3
100
100
100
N.A.
93.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.2
N.A.
30.9
Protein Similarity:
N.A.
N.A.
N.A.
52.4
N.A.
47.9
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
0
16
0
8
0
0
0
0
0
85
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
8
0
0
0
0
8
0
8
0
% D
% Glu:
0
8
77
0
0
8
0
0
0
8
0
93
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
24
0
0
77
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
85
0
8
0
0
8
8
% I
% Lys:
0
8
8
0
0
85
0
0
0
0
8
0
0
0
85
% K
% Leu:
0
8
0
0
16
0
0
0
8
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
70
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
70
0
0
0
0
0
70
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
70
0
93
0
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _