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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAF4 All Species: 8.48
Human Site: S678 Identified Species: 15.56
UniProt: O00268 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00268 NP_003176.2 1085 110114 S678 S A A F I Q Q S Q Q Q P P P P
Chimpanzee Pan troglodytes XP_514759 496 54508 Q156 P T P L V I Q Q P P K P G A L
Rhesus Macaque Macaca mulatta XP_001115352 650 70060 Q310 P T P L V I Q Q P P K P G A L
Dog Lupus familis XP_534471 795 85047 Q455 P T P L V I Q Q P P K P G A L
Cat Felis silvestris
Mouse Mus musculus Q8VIJ6 699 75423 A359 R Q L R V R F A T H A A A L S
Rat Rattus norvegicus XP_001073245 857 89852 Q517 P Q S A G I P Q A G K A K Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505778 922 96249 S560 T L Q Q P V I S L T Q P T Q V
Chicken Gallus gallus XP_417400 1101 114279 S696 S A A F I Q Q S Q Q Q Q P T T
Frog Xenopus laevis NP_001091268 1016 107092 S616 A A A F I Q Q S Q Q Q Q P H T
Zebra Danio Brachydanio rerio XP_001920944 732 76077 K392 V K N L L E G K I E A E E F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P47825 921 99320 L562 T T L P I P S L P T V H L P P
Honey Bee Apis mellifera XP_392451 937 100623 A584 T P T T V P V A A V T A S T Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782176 689 73135 A349 G S K Q S Q Q A S Q K H S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.6 59.3 67 N.A. 20.3 30.8 N.A. 68.3 69 64.7 41.3 N.A. 27.1 30 N.A. 31.5
Protein Similarity: 100 45.6 59.5 68.9 N.A. 32.2 43.7 N.A. 72 75.3 71.5 50.4 N.A. 39.5 44.2 N.A. 42.4
P-Site Identity: 100 13.3 13.3 13.3 N.A. 0 0 N.A. 20 80 73.3 0 N.A. 20 0 N.A. 20
P-Site Similarity: 100 26.6 26.6 26.6 N.A. 20 13.3 N.A. 26.6 80 80 20 N.A. 26.6 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 24 24 8 0 0 0 24 16 0 16 24 8 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 8 0 8 8 0 0 % E
% Phe: 0 0 0 24 0 0 8 0 0 0 0 0 0 8 0 % F
% Gly: 8 0 0 0 8 0 8 0 0 8 0 0 24 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 16 0 8 0 % H
% Ile: 0 0 0 0 31 31 8 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 0 8 0 0 39 0 8 0 0 % K
% Leu: 0 8 16 31 8 0 0 8 8 0 0 0 8 8 31 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 31 8 24 8 8 16 8 0 31 24 0 39 24 16 16 % P
% Gln: 0 16 8 16 0 31 54 31 24 31 31 16 0 16 8 % Q
% Arg: 8 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 8 8 0 8 0 8 31 8 0 0 0 16 8 16 % S
% Thr: 24 31 8 8 0 0 0 0 8 16 8 0 8 16 24 % T
% Val: 8 0 0 0 39 8 8 0 0 8 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _