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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAF4
All Species:
6.67
Human Site:
T494
Identified Species:
12.22
UniProt:
O00268
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00268
NP_003176.2
1085
110114
T494
T
M
A
P
R
P
A
T
P
T
S
A
P
P
V
Chimpanzee
Pan troglodytes
XP_514759
496
54508
Rhesus Macaque
Macaca mulatta
XP_001115352
650
70060
Q133
L
G
T
A
T
A
V
Q
T
G
T
P
Q
R
T
Dog
Lupus familis
XP_534471
795
85047
V278
S
L
G
T
A
T
A
V
Q
T
G
T
P
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ6
699
75423
P182
T
G
G
P
P
P
P
P
A
G
G
A
G
P
G
Rat
Rattus norvegicus
XP_001073245
857
89852
T340
L
P
N
S
Q
S
F
T
E
N
C
V
Q
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505778
922
96249
R381
Q
P
T
T
T
L
Q
R
P
P
V
V
Q
P
Q
Chicken
Gallus gallus
XP_417400
1101
114279
T512
T
M
T
P
R
P
A
T
P
T
S
A
P
P
V
Frog
Xenopus laevis
NP_001091268
1016
107092
A432
N
T
M
V
P
R
P
A
T
P
T
S
A
P
P
Zebra Danio
Brachydanio rerio
XP_001920944
732
76077
R215
A
P
Q
V
L
A
P
R
L
P
Q
S
S
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P47825
921
99320
P380
V
I
E
G
I
K
P
P
P
Q
H
V
L
G
L
Honey Bee
Apis mellifera
XP_392451
937
100623
A404
I
V
D
F
L
V
Y
A
I
S
W
N
G
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782176
689
73135
S172
T
V
F
R
G
A
T
S
A
N
A
S
L
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.6
59.3
67
N.A.
20.3
30.8
N.A.
68.3
69
64.7
41.3
N.A.
27.1
30
N.A.
31.5
Protein Similarity:
100
45.6
59.5
68.9
N.A.
32.2
43.7
N.A.
72
75.3
71.5
50.4
N.A.
39.5
44.2
N.A.
42.4
P-Site Identity:
100
0
0
20
N.A.
33.3
13.3
N.A.
13.3
93.3
6.6
6.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
0
6.6
33.3
N.A.
33.3
20
N.A.
13.3
93.3
20
13.3
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
24
24
16
16
0
8
24
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
16
8
8
0
0
0
0
16
16
0
16
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
8
0
0
16
8
0
0
8
0
0
0
16
0
8
% L
% Met:
0
16
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
16
0
8
0
0
0
% N
% Pro:
0
24
0
24
16
24
31
16
31
24
0
8
24
47
8
% P
% Gln:
8
0
8
0
8
0
8
8
8
8
8
0
24
16
16
% Q
% Arg:
0
0
0
8
16
8
0
16
0
0
0
0
0
8
8
% R
% Ser:
8
0
0
8
0
8
0
8
0
8
16
24
8
0
0
% S
% Thr:
31
8
24
16
16
8
8
24
16
24
16
8
0
0
8
% T
% Val:
8
16
0
16
0
8
8
8
0
0
8
24
0
8
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _