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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DFFA
All Species:
10.91
Human Site:
S12
Identified Species:
34.29
UniProt:
O00273
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00273
NP_004392.1
331
36522
S12
G
D
A
G
V
P
E
S
G
E
I
R
T
L
K
Chimpanzee
Pan troglodytes
XP_001161941
331
36301
S12
G
D
A
G
V
P
E
S
G
E
S
R
T
L
K
Rhesus Macaque
Macaca mulatta
XP_001102195
331
36592
S12
G
D
A
G
V
P
E
S
G
E
I
R
T
L
K
Dog
Lupus familis
XP_544574
326
35493
T13
A
A
E
A
E
T
R
T
L
K
P
C
V
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O54786
331
36542
P12
R
G
A
S
A
P
D
P
D
D
V
R
P
L
K
Rat
Rattus norvegicus
Q99N34
349
40078
H17
C
V
K
L
R
A
L
H
S
S
C
K
F
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509884
656
71965
S339
D
M
D
T
S
G
G
S
A
D
N
L
D
P
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120965
204
22431
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
93.9
77
N.A.
76.1
23.2
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
100
97.5
96.6
85.8
N.A.
87.9
42.4
N.A.
41.9
N.A.
N.A.
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
100
93.3
100
6.6
N.A.
33.3
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
93.3
100
26.6
N.A.
53.3
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
50
13
13
13
0
0
13
0
0
0
0
0
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
13
13
0
0
0
% C
% Asp:
13
38
13
0
0
0
13
0
13
25
0
0
13
0
0
% D
% Glu:
0
0
13
0
13
0
38
0
0
38
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
38
13
0
38
0
13
13
0
38
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
13
0
13
0
0
63
% K
% Leu:
0
0
0
13
0
0
13
0
13
0
0
13
0
63
0
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
50
0
13
0
0
13
0
13
13
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
13
0
13
0
0
0
0
50
0
0
13
% R
% Ser:
0
0
0
13
13
0
0
50
13
13
13
0
0
0
0
% S
% Thr:
0
0
0
13
0
13
0
13
0
0
0
0
38
0
0
% T
% Val:
0
13
0
0
38
0
0
0
0
0
13
0
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _