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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIP1 All Species: 31.21
Human Site: S302 Identified Species: 52.82
UniProt: O00291 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00291 NP_005329.3 1037 116221 S302 P P N F L R A S A L S E H I S
Chimpanzee Pan troglodytes XP_001175228 535 60449
Rhesus Macaque Macaca mulatta XP_001109894 1037 116235 S302 P P N F L R A S A L S E H I S
Dog Lupus familis XP_546932 1036 116372 S302 P P N F L R A S A L S E H I S
Cat Felis silvestris
Mouse Mus musculus Q8VD75 1029 115184 S302 P P N F L R A S A L S E H I S
Rat Rattus norvegicus NP_001093945 1030 114985 S302 P P N F L R A S A L S E H I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506915 1061 119171 S286 P P N F L R A S A L A E H I K
Chicken Gallus gallus XP_001232953 1018 113964 L298 P E N P P N F L R A S A L S E
Frog Xenopus laevis NP_001086615 1066 120922 S293 P P N F L R A S A L A E H V K
Zebra Danio Brachydanio rerio NP_001159677 1046 116144 S302 P P N F L R A S A L S E H I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394258 927 105031 N269 T I P T L P E N P P N F L V Q
Nematode Worm Caenorhab. elegans Q02328 927 104410 H269 S I P T L P S H A P N F L Q Q
Sea Urchin Strong. purpuratus XP_785542 970 108923 P293 L I Q V P T L P A E P P N F F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33338 968 108893 R289 E P S V T P A R T P A R T P T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.2 98.2 90.4 N.A. 87.8 87.6 N.A. 50.7 78.5 51.5 68.1 N.A. N.A. 37.6 34.1 38.1
Protein Similarity: 100 51.5 99.3 95.4 N.A. 93.2 92.9 N.A. 67.3 87.8 69.7 81 N.A. N.A. 56.8 53 57.9
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 86.6 20 80 100 N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 93.3 20 93.3 100 N.A. N.A. 26.6 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 65 0 72 8 22 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 8 0 0 0 0 8 0 0 8 0 58 0 0 8 % E
% Phe: 0 0 0 58 0 0 8 0 0 0 0 15 0 8 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 58 0 0 % H
% Ile: 0 22 0 0 0 0 0 0 0 0 0 0 0 50 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 8 0 0 0 72 0 8 8 0 58 0 0 22 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 65 0 0 8 0 8 0 0 15 0 8 0 0 % N
% Pro: 65 65 15 8 15 22 0 8 8 22 8 8 0 8 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 15 % Q
% Arg: 0 0 0 0 0 58 0 8 8 0 0 8 0 0 0 % R
% Ser: 8 0 8 0 0 0 8 58 0 0 50 0 0 8 43 % S
% Thr: 8 0 0 15 8 8 0 0 8 0 0 0 8 0 8 % T
% Val: 0 0 0 15 0 0 0 0 0 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _