Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIP1 All Species: 22.42
Human Site: S398 Identified Species: 37.95
UniProt: O00291 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00291 NP_005329.3 1037 116221 S398 L E N M K T E S Q R V V L Q L
Chimpanzee Pan troglodytes XP_001175228 535 60449
Rhesus Macaque Macaca mulatta XP_001109894 1037 116235 S398 L E N M K T E S Q R V V L Q L
Dog Lupus familis XP_546932 1036 116372 S398 L G S M K T E S Q R A V L Q L
Cat Felis silvestris
Mouse Mus musculus Q8VD75 1029 115184 S398 L D N M K I E S Q R A M L Q L
Rat Rattus norvegicus NP_001093945 1030 114985 S398 L D N V K I E S Q R A M L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506915 1061 119171 L388 V N E L E T E L E E Q R Q Q K
Chicken Gallus gallus XP_001232953 1018 113964 S394 L E S F K A E S E R R G L Q L
Frog Xenopus laevis NP_001086615 1066 120922 G387 K Y I L Q L K G Q I N T L E A
Zebra Danio Brachydanio rerio NP_001159677 1046 116144 S399 L E S F R L E S G R L C Q A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394258 927 105031 V363 L T D H Q R I V E E L Q I H V
Nematode Worm Caenorhab. elegans Q02328 927 104410 L363 I E Q Y E N R L L Q M Q G E F
Sea Urchin Strong. purpuratus XP_785542 970 108923 R387 Q Q S G P D E R D W I I E Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33338 968 108893 Q385 R V Q Q L Q Q Q Q A Q Q E L F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.2 98.2 90.4 N.A. 87.8 87.6 N.A. 50.7 78.5 51.5 68.1 N.A. N.A. 37.6 34.1 38.1
Protein Similarity: 100 51.5 99.3 95.4 N.A. 93.2 92.9 N.A. 67.3 87.8 69.7 81 N.A. N.A. 56.8 53 57.9
P-Site Identity: 100 0 100 80 N.A. 73.3 66.6 N.A. 20 60 13.3 40 N.A. N.A. 6.6 6.6 20
P-Site Similarity: 100 0 100 86.6 N.A. 86.6 86.6 N.A. 46.6 73.3 40 60 N.A. N.A. 46.6 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 8 22 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 15 8 0 0 8 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 36 8 0 15 0 65 0 22 15 0 0 15 15 0 % E
% Phe: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 15 % F
% Gly: 0 8 0 8 0 0 0 8 8 0 0 8 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 8 0 0 15 8 0 0 8 8 8 8 0 0 % I
% Lys: 8 0 0 0 43 0 8 0 0 0 0 0 0 0 8 % K
% Leu: 58 0 0 15 8 15 0 15 8 0 15 0 50 8 58 % L
% Met: 0 0 0 29 0 0 0 0 0 0 8 15 0 0 0 % M
% Asn: 0 8 29 0 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 8 15 8 15 8 8 8 50 8 15 22 15 58 0 % Q
% Arg: 8 0 0 0 8 8 8 8 0 50 8 8 0 0 0 % R
% Ser: 0 0 29 0 0 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 0 29 0 0 0 0 0 8 0 0 0 % T
% Val: 8 8 0 8 0 0 0 8 0 0 15 22 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _