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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1
All Species:
22.12
Human Site:
S43
Identified Species:
37.44
UniProt:
O00291
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00291
NP_005329.3
1037
116221
S43
F
E
R
T
Q
T
V
S
I
N
K
A
I
N
T
Chimpanzee
Pan troglodytes
XP_001175228
535
60449
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
S43
F
E
R
T
Q
T
V
S
I
N
K
A
I
N
T
Dog
Lupus familis
XP_546932
1036
116372
S43
F
E
R
T
Q
T
V
S
I
N
K
A
I
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VD75
1029
115184
S43
F
E
R
T
Q
T
V
S
V
N
K
A
I
N
T
Rat
Rattus norvegicus
NP_001093945
1030
114985
S43
F
E
R
T
Q
T
V
S
V
N
K
A
I
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
H43
E
A
P
V
K
E
K
H
A
R
R
I
I
L
G
Chicken
Gallus gallus
XP_001232953
1018
113964
I43
E
R
A
Q
T
V
S
I
N
K
A
I
N
T
Q
Frog
Xenopus laevis
NP_001086615
1066
120922
P45
A
I
N
T
Q
E
A
P
V
K
E
K
H
A
R
Zebra Danio
Brachydanio rerio
NP_001159677
1046
116144
S43
F
E
R
N
Q
A
V
S
I
N
K
A
I
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394258
927
105031
K31
N
P
T
E
T
P
V
K
E
K
H
V
R
S
A
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
K31
T
K
N
E
V
P
L
K
P
K
H
A
R
T
I
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
F53
K
E
K
H
V
R
S
F
L
N
Y
A
S
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
A43
W
D
H
Q
S
S
K
A
V
F
T
T
L
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
98.2
90.4
N.A.
87.8
87.6
N.A.
50.7
78.5
51.5
68.1
N.A.
N.A.
37.6
34.1
38.1
Protein Similarity:
100
51.5
99.3
95.4
N.A.
93.2
92.9
N.A.
67.3
87.8
69.7
81
N.A.
N.A.
56.8
53
57.9
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
6.6
0
13.3
86.6
N.A.
N.A.
6.6
6.6
20
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
20
0
26.6
86.6
N.A.
N.A.
13.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
8
8
8
0
8
58
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
15
50
0
15
0
15
0
0
8
0
8
0
0
0
0
% E
% Phe:
43
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
8
8
0
0
0
8
0
0
15
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
29
0
0
15
50
0
8
% I
% Lys:
8
8
8
0
8
0
15
15
0
29
43
8
0
8
0
% K
% Leu:
0
0
0
0
0
0
8
0
8
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
15
8
0
0
0
0
8
50
0
0
8
43
0
% N
% Pro:
0
8
8
0
0
15
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
50
0
0
0
0
0
0
0
0
0
15
% Q
% Arg:
0
8
43
0
0
8
0
0
0
8
8
0
15
0
8
% R
% Ser:
0
0
0
0
8
8
15
43
0
0
0
0
8
15
0
% S
% Thr:
8
0
8
43
15
36
0
0
0
0
8
8
0
15
50
% T
% Val:
0
0
0
8
15
8
50
0
29
0
0
8
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _