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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1
All Species:
15.15
Human Site:
S521
Identified Species:
25.64
UniProt:
O00291
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00291
NP_005329.3
1037
116221
S521
E
D
S
L
E
R
I
S
D
Q
G
Q
R
K
T
Chimpanzee
Pan troglodytes
XP_001175228
535
60449
P66
P
Q
L
P
E
N
P
P
N
F
L
R
A
S
A
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
S521
E
D
S
L
E
R
I
S
D
Q
G
Q
R
K
T
Dog
Lupus familis
XP_546932
1036
116372
S521
E
D
S
F
Q
R
I
S
D
Q
A
Q
R
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VD75
1029
115184
L513
L
E
R
E
K
K
E
L
A
D
S
F
A
R
T
Rat
Rattus norvegicus
NP_001093945
1030
114985
L513
L
E
R
E
K
K
E
L
A
D
S
F
A
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
K493
A
F
Q
M
E
Q
V
K
R
E
S
D
M
K
L
Chicken
Gallus gallus
XP_001232953
1018
113964
S517
E
D
S
F
Q
R
V
S
E
Q
S
Q
R
K
S
Frog
Xenopus laevis
NP_001086615
1066
120922
K501
E
F
Q
M
D
Q
V
K
R
E
S
D
L
K
L
Zebra Danio
Brachydanio rerio
NP_001159677
1046
116144
Q522
Q
D
R
L
K
V
A
Q
D
S
A
S
Q
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394258
927
105031
Q458
R
K
K
T
V
E
A
Q
H
D
L
D
D
V
K
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
K458
S
E
K
S
K
F
D
K
D
E
E
I
T
A
L
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
K482
V
N
E
E
R
F
K
K
M
K
D
V
Y
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
Y485
Y
E
S
L
A
K
L
Y
S
Q
L
R
Q
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
98.2
90.4
N.A.
87.8
87.6
N.A.
50.7
78.5
51.5
68.1
N.A.
N.A.
37.6
34.1
38.1
Protein Similarity:
100
51.5
99.3
95.4
N.A.
93.2
92.9
N.A.
67.3
87.8
69.7
81
N.A.
N.A.
56.8
53
57.9
P-Site Identity:
100
6.6
100
80
N.A.
6.6
6.6
N.A.
13.3
60
13.3
20
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
20
100
86.6
N.A.
33.3
33.3
N.A.
40
86.6
46.6
46.6
N.A.
N.A.
0
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
15
0
15
0
15
0
22
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
36
0
0
8
0
8
0
36
22
8
22
8
0
0
% D
% Glu:
36
29
8
22
29
8
15
0
8
22
8
0
0
8
8
% E
% Phe:
0
15
0
15
0
15
0
0
0
8
0
15
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
22
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
15
0
29
22
8
29
0
8
0
0
0
43
15
% K
% Leu:
15
0
8
29
0
0
8
15
0
0
22
0
8
0
22
% L
% Met:
0
0
0
15
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
8
0
0
0
0
8
0
% N
% Pro:
8
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% P
% Gln:
8
8
15
0
15
15
0
15
0
36
0
29
15
8
0
% Q
% Arg:
8
0
22
0
8
29
0
0
15
0
0
15
29
15
0
% R
% Ser:
8
0
36
8
0
0
0
29
8
8
36
8
0
8
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
36
% T
% Val:
8
0
0
0
8
8
22
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _