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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1
All Species:
26.97
Human Site:
S559
Identified Species:
45.64
UniProt:
O00291
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00291
NP_005329.3
1037
116221
S559
L
Q
G
S
L
E
T
S
A
Q
S
E
A
N
W
Chimpanzee
Pan troglodytes
XP_001175228
535
60449
D104
L
E
K
D
D
L
M
D
M
D
A
S
Q
Q
N
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
S559
L
Q
G
S
L
E
T
S
A
Q
S
E
A
N
W
Dog
Lupus familis
XP_546932
1036
116372
S559
V
Q
G
S
L
E
T
S
A
Q
S
E
A
K
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8VD75
1029
115184
S551
L
H
S
N
L
E
T
S
A
Q
S
E
A
K
W
Rat
Rattus norvegicus
NP_001093945
1030
114985
S551
L
H
G
N
L
E
T
S
A
Q
S
E
A
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
S531
V
Q
E
T
L
S
H
S
E
Q
S
G
S
E
L
Chicken
Gallus gallus
XP_001232953
1018
113964
T555
L
Q
G
T
L
E
T
T
I
Q
V
G
A
E
Q
Frog
Xenopus laevis
NP_001086615
1066
120922
T539
I
Q
Q
S
L
S
N
T
E
E
T
K
S
Q
L
Zebra Danio
Brachydanio rerio
NP_001159677
1046
116144
S560
L
K
S
T
V
T
S
S
Q
Q
S
N
E
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394258
927
105031
I496
K
M
A
L
E
G
D
I
H
D
L
L
A
Q
K
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
Q496
A
V
D
E
M
R
T
Q
L
V
K
A
D
I
E
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
L520
K
C
S
E
E
T
V
L
A
R
Q
T
A
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
L523
K
E
Q
L
E
H
K
L
K
Q
K
D
L
Q
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
98.2
90.4
N.A.
87.8
87.6
N.A.
50.7
78.5
51.5
68.1
N.A.
N.A.
37.6
34.1
38.1
Protein Similarity:
100
51.5
99.3
95.4
N.A.
93.2
92.9
N.A.
67.3
87.8
69.7
81
N.A.
N.A.
56.8
53
57.9
P-Site Identity:
100
6.6
100
86.6
N.A.
73.3
80
N.A.
33.3
53.3
20
26.6
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
20
100
93.3
N.A.
80
86.6
N.A.
53.3
66.6
60
53.3
N.A.
N.A.
6.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
43
0
8
8
58
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
8
0
8
8
0
15
0
8
8
0
0
% D
% Glu:
0
15
8
15
22
43
0
0
15
8
0
36
8
22
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
36
0
0
8
0
0
0
0
0
15
0
0
0
% G
% His:
0
15
0
0
0
8
8
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% I
% Lys:
22
8
8
0
0
0
8
0
8
0
15
8
0
22
8
% K
% Leu:
50
0
0
15
58
8
0
15
8
0
8
8
8
0
22
% L
% Met:
0
8
0
0
8
0
8
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
0
15
0
0
8
0
0
0
0
8
0
15
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
43
15
0
0
0
0
8
8
65
8
0
8
36
15
% Q
% Arg:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
22
29
0
15
8
50
0
0
50
8
15
0
0
% S
% Thr:
0
0
0
22
0
15
50
15
0
0
8
8
0
0
0
% T
% Val:
15
8
0
0
8
0
8
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _