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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1
All Species:
22.73
Human Site:
S649
Identified Species:
38.46
UniProt:
O00291
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00291
NP_005329.3
1037
116221
S649
L
E
E
P
P
L
I
S
C
A
G
S
A
D
H
Chimpanzee
Pan troglodytes
XP_001175228
535
60449
A184
G
H
V
S
E
L
E
A
E
L
A
E
Q
Q
H
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
S649
L
E
E
P
P
L
I
S
C
A
G
S
A
D
H
Dog
Lupus familis
XP_546932
1036
116372
S649
L
E
E
P
T
L
I
S
C
A
G
S
A
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VD75
1029
115184
S641
L
E
E
P
T
L
I
S
C
A
G
S
T
D
H
Rat
Rattus norvegicus
NP_001093945
1030
114985
S642
E
E
P
A
L
L
I
S
C
A
G
A
T
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
R642
L
D
D
P
L
H
V
R
C
T
C
S
P
D
Y
Chicken
Gallus gallus
XP_001232953
1018
113964
S643
L
E
D
P
A
H
I
S
C
T
G
S
A
D
Y
Frog
Xenopus laevis
NP_001086615
1066
120922
R650
L
D
D
P
L
H
I
R
C
T
S
S
P
D
Y
Zebra Danio
Brachydanio rerio
NP_001159677
1046
116144
S671
L
E
D
P
A
H
I
S
C
T
S
S
A
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394258
927
105031
I576
L
E
K
L
E
D
P
I
L
K
S
L
D
A
L
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
M576
P
H
L
A
Q
S
A
M
N
N
L
V
N
I
L
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
E600
S
R
A
P
I
A
D
E
C
V
N
N
L
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
F607
G
P
L
T
P
P
T
F
L
L
S
L
L
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
98.2
90.4
N.A.
87.8
87.6
N.A.
50.7
78.5
51.5
68.1
N.A.
N.A.
37.6
34.1
38.1
Protein Similarity:
100
51.5
99.3
95.4
N.A.
93.2
92.9
N.A.
67.3
87.8
69.7
81
N.A.
N.A.
56.8
53
57.9
P-Site Identity:
100
13.3
100
93.3
N.A.
86.6
60
N.A.
33.3
66.6
40
60
N.A.
N.A.
13.3
0
13.3
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
66.6
N.A.
60
80
60
73.3
N.A.
N.A.
20
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
15
8
8
8
0
36
8
8
36
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
72
0
8
0
0
0
0
% C
% Asp:
0
15
29
0
0
8
8
0
0
0
0
0
8
65
0
% D
% Glu:
8
58
29
0
15
0
8
8
8
0
0
8
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% G
% His:
0
15
0
0
0
29
0
0
0
0
0
0
0
0
43
% H
% Ile:
0
0
0
0
8
0
58
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
65
0
15
8
22
43
0
0
15
15
8
15
15
0
15
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
8
8
8
0
0
% N
% Pro:
8
8
8
65
22
8
8
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
8
0
0
0
0
0
15
0
0
0
0
0
0
8
% R
% Ser:
8
0
0
8
0
8
0
50
0
0
29
58
0
0
8
% S
% Thr:
0
0
0
8
15
0
8
0
0
29
0
0
15
0
0
% T
% Val:
0
0
8
0
0
0
8
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _