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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIP1
All Species:
18.18
Human Site:
Y152
Identified Species:
30.77
UniProt:
O00291
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00291
NP_005329.3
1037
116221
Y152
L
L
R
T
K
M
E
Y
H
T
K
N
P
R
F
Chimpanzee
Pan troglodytes
XP_001175228
535
60449
Rhesus Macaque
Macaca mulatta
XP_001109894
1037
116235
Y152
L
L
R
T
K
M
E
Y
H
T
K
N
P
R
F
Dog
Lupus familis
XP_546932
1036
116372
Y152
L
L
R
T
K
M
E
Y
H
T
K
N
P
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VD75
1029
115184
Y152
L
L
R
T
R
M
E
Y
H
T
K
N
P
R
F
Rat
Rattus norvegicus
NP_001093945
1030
114985
Y152
L
L
R
T
R
M
E
Y
H
T
K
N
P
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506915
1061
119171
H140
K
I
S
F
H
L
K
H
P
Q
F
P
P
G
L
Chicken
Gallus gallus
XP_001232953
1018
113964
F151
L
L
R
T
K
M
E
F
H
T
K
N
P
R
F
Frog
Xenopus laevis
NP_001086615
1066
120922
F143
L
L
L
N
K
I
S
F
H
V
K
H
P
E
F
Zebra Danio
Brachydanio rerio
NP_001159677
1046
116144
F152
L
L
I
T
K
M
E
F
H
I
K
N
P
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394258
927
105031
H128
L
I
T
K
L
D
F
H
K
R
N
P
R
I
P
Nematode Worm
Caenorhab. elegans
Q02328
927
104410
F128
L
L
H
D
R
V
T
F
H
N
K
Y
P
V
V
Sea Urchin
Strong. purpuratus
XP_785542
970
108923
F151
L
L
N
T
K
L
E
F
H
K
K
N
P
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33338
968
108893
E147
V
S
V
S
D
P
D
E
G
Y
E
T
I
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
98.2
90.4
N.A.
87.8
87.6
N.A.
50.7
78.5
51.5
68.1
N.A.
N.A.
37.6
34.1
38.1
Protein Similarity:
100
51.5
99.3
95.4
N.A.
93.2
92.9
N.A.
67.3
87.8
69.7
81
N.A.
N.A.
56.8
53
57.9
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
6.6
93.3
46.6
80
N.A.
N.A.
6.6
33.3
60
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
33.3
100
66.6
86.6
N.A.
N.A.
20
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
8
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
58
8
0
0
8
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
8
36
0
0
8
0
0
0
58
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
0
8
0
8
0
0
15
72
0
0
8
0
0
0
% H
% Ile:
0
15
8
0
0
8
0
0
0
8
0
0
8
8
0
% I
% Lys:
8
0
0
8
50
0
8
0
8
8
72
0
0
0
0
% K
% Leu:
79
72
8
0
8
15
0
0
0
0
0
0
0
15
15
% L
% Met:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
8
8
58
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
8
0
0
15
79
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
43
0
22
0
0
0
0
8
0
0
8
50
0
% R
% Ser:
0
8
8
8
0
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
58
0
0
8
0
0
43
0
8
0
0
0
% T
% Val:
8
0
8
0
0
8
0
0
0
8
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _