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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEFTY2
All Species:
20.61
Human Site:
S352
Identified Species:
45.33
UniProt:
O00292
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00292
NP_003231.2
366
40920
S352
N
M
R
V
Q
K
C
S
C
A
S
D
G
A
L
Chimpanzee
Pan troglodytes
XP_001138066
366
40871
S352
N
M
R
V
Q
K
C
S
C
A
S
D
G
A
L
Rhesus Macaque
Macaca mulatta
XP_001092296
366
40758
S352
N
M
R
V
Q
K
C
S
C
A
S
D
G
A
L
Dog
Lupus familis
XP_547508
410
45569
S396
N
M
R
V
Q
K
C
S
C
S
W
D
G
M
P
Cat
Felis silvestris
Mouse
Mus musculus
P57785
368
41157
S354
N
M
R
V
Q
T
C
S
C
A
S
D
G
A
L
Rat
Rattus norvegicus
Q06826
408
46522
D390
M
L
Y
L
D
E
Y
D
K
V
V
L
K
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512708
369
41483
G346
N
M
N
V
L
K
C
G
C
V
S
S
G
S
R
Chicken
Gallus gallus
NP_990095
362
41161
S349
N
M
I
I
E
K
C
S
C
M
A
D
G
A
D
Frog
Xenopus laevis
P25703
398
45557
V382
Y
L
D
E
N
E
K
V
V
L
K
N
Y
Q
D
Zebra Danio
Brachydanio rerio
NP_571036
362
41441
C352
P
N
M
I
V
E
K
C
G
C
S
M
D
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123281
399
44790
N389
L
K
V
E
E
I
P
N
M
I
V
E
D
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
72.1
N.A.
81.2
21.3
N.A.
43.3
38.7
21.1
37.1
N.A.
N.A.
N.A.
N.A.
22
Protein Similarity:
100
96.4
96.1
79.5
N.A.
89.1
35.5
N.A.
60.4
57.3
37.1
59.2
N.A.
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
100
100
73.3
N.A.
93.3
0
N.A.
53.3
60
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
93.3
20
N.A.
60
80
20
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
37
10
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
64
10
64
10
0
0
0
10
0
% C
% Asp:
0
0
10
0
10
0
0
10
0
0
0
55
19
0
19
% D
% Glu:
0
0
0
19
19
28
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
0
0
0
64
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
19
0
10
0
0
0
10
0
0
0
0
10
% I
% Lys:
0
10
0
0
0
55
19
0
10
0
10
0
10
10
0
% K
% Leu:
10
19
0
10
10
0
0
0
0
10
0
10
0
0
37
% L
% Met:
10
64
10
0
0
0
0
0
10
10
0
10
0
10
0
% M
% Asn:
64
10
10
0
10
0
0
10
0
0
0
10
0
10
0
% N
% Pro:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
46
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
55
0
10
55
10
0
10
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
55
10
0
0
10
10
19
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
10
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _