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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TULP1
All Species:
20.91
Human Site:
Y518
Identified Species:
41.82
UniProt:
O00294
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00294
NP_003313.3
542
60609
Y518
E
D
A
F
T
L
D
Y
R
Y
P
L
C
A
L
Chimpanzee
Pan troglodytes
XP_001172351
542
60606
Y518
E
D
A
F
T
L
D
Y
R
Y
P
L
C
A
L
Rhesus Macaque
Macaca mulatta
XP_001111988
1010
112638
P514
R
L
L
N
T
N
F
P
S
R
S
L
P
P
P
Dog
Lupus familis
XP_538879
920
102181
E868
H
K
L
K
H
L
P
E
K
Y
M
M
N
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z273
543
60317
Y519
E
D
A
F
T
L
D
Y
R
Y
P
L
C
A
L
Rat
Rattus norvegicus
O88808
505
55299
Y481
E
D
V
F
T
M
D
Y
N
Y
P
L
C
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518309
170
19113
R147
D
T
F
T
L
D
Y
R
Y
P
L
C
A
L
Q
Chicken
Gallus gallus
NP_989946
358
40105
N335
D
A
F
T
M
D
Y
N
Y
P
L
C
A
V
Q
Frog
Xenopus laevis
NP_001086168
505
56501
Y481
E
D
V
F
T
M
D
Y
N
Y
P
M
C
A
L
Zebra Danio
Brachydanio rerio
XP_697114
530
58796
Y506
E
D
V
F
T
M
D
Y
N
Y
P
M
C
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09306
426
48435
R403
D
E
F
T
M
D
F
R
Y
P
L
S
A
V
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VY21
406
45293
Q383
D
V
F
T
M
D
Y
Q
Y
P
I
S
A
F
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
49.7
21.2
N.A.
78.8
45.5
N.A.
27.4
46.4
44.8
44
N.A.
N.A.
N.A.
36.9
N.A.
Protein Similarity:
100
99.4
50.8
34.2
N.A.
86.5
59
N.A.
29.5
56.2
59.4
57.9
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
100
80
N.A.
0
0
73.3
73.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
13.3
40
N.A.
100
86.6
N.A.
6.6
6.6
86.6
86.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
0
0
0
0
0
0
0
0
0
34
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
17
50
0
0
% C
% Asp:
34
50
0
0
0
34
50
0
0
0
0
0
0
0
0
% D
% Glu:
50
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
34
50
0
0
17
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
9
0
9
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
9
17
0
9
34
0
0
0
0
25
42
0
9
50
% L
% Met:
0
0
0
0
25
25
0
0
0
0
9
25
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
9
25
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
9
9
0
34
50
0
9
9
9
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
34
% Q
% Arg:
9
0
0
0
0
0
0
17
25
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
0
9
17
0
9
0
% S
% Thr:
0
9
0
34
59
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
25
0
0
0
0
0
0
0
0
0
0
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
25
50
34
59
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _