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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TULP2
All Species:
1.82
Human Site:
S250
Identified Species:
3.64
UniProt:
O00295
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00295
NP_003314.2
520
58664
S250
K
G
E
G
G
T
D
S
D
H
M
R
H
E
A
Chimpanzee
Pan troglodytes
XP_521835
552
60170
R275
A
T
S
R
K
S
V
R
E
A
A
S
A
P
S
Rhesus Macaque
Macaca mulatta
XP_001104584
506
55633
R229
A
T
S
R
K
S
V
R
E
A
A
S
A
P
S
Dog
Lupus familis
XP_541507
474
52282
P207
S
P
L
R
A
P
G
P
R
L
G
Q
D
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P46686
562
62706
N286
G
D
D
G
D
A
S
N
H
N
A
W
N
M
T
Rat
Rattus norvegicus
O88808
505
55299
R228
A
T
S
R
K
S
T
R
E
A
A
S
A
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508810
461
50869
E203
A
T
A
G
T
L
G
E
V
E
N
L
E
D
F
Chicken
Gallus gallus
XP_420992
506
56544
S230
G
S
A
T
S
K
K
S
S
K
E
V
A
S
A
Frog
Xenopus laevis
NP_001086168
505
56501
S229
G
S
A
T
S
K
K
S
H
K
E
T
V
S
A
Zebra Danio
Brachydanio rerio
XP_697114
530
58796
S254
G
S
A
T
S
K
K
S
S
K
E
A
T
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09306
426
48435
A168
N
F
I
K
N
N
L
A
K
F
V
E
D
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VY21
406
45293
N148
G
L
N
Q
A
A
S
N
D
D
G
K
F
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32
36.9
57.5
N.A.
53.3
37.3
N.A.
39.6
38
38.8
35.4
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
100
50.7
57.1
67.6
N.A.
66.1
56.1
N.A.
55.1
57.6
57.8
53.4
N.A.
N.A.
N.A.
53.8
N.A.
P-Site Identity:
100
0
0
0
N.A.
6.6
0
N.A.
6.6
13.3
13.3
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
20
6.6
N.A.
33.3
20
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
34
0
17
17
0
9
0
25
34
9
34
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
0
9
0
17
9
0
0
17
9
0
% D
% Glu:
0
0
9
0
0
0
0
9
25
9
25
9
9
9
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
9
% F
% Gly:
42
9
0
25
9
0
17
0
0
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
17
9
0
0
9
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
9
25
25
25
0
9
25
0
9
0
0
0
% K
% Leu:
0
9
9
0
0
9
9
0
0
9
0
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% M
% Asn:
9
0
9
0
9
9
0
17
0
9
9
0
9
0
0
% N
% Pro:
0
9
0
0
0
9
0
9
0
0
0
0
0
34
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
34
0
0
0
25
9
0
0
9
0
0
0
% R
% Ser:
9
25
25
0
25
25
17
34
17
0
0
25
0
25
25
% S
% Thr:
0
34
0
25
9
9
9
0
0
0
0
9
9
9
9
% T
% Val:
0
0
0
0
0
0
17
0
9
0
9
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _