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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WWP2 All Species: 19.7
Human Site: S104 Identified Species: 39.39
UniProt: O00308 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00308 NP_008945.2 870 98912 S104 G T A S V N L S N V L K N N G
Chimpanzee Pan troglodytes XP_519843 922 105197 A104 A T I D L K Q A L L I H N R K
Rhesus Macaque Macaca mulatta XP_001101869 870 98735 S104 G T A S V N L S N V L K N N G
Dog Lupus familis XP_851140 922 104001 S104 G T A S V N L S N V L K N N G
Cat Felis silvestris
Mouse Mus musculus Q9DBH0 870 98742 S104 G T A S V N L S N V L K N N G
Rat Rattus norvegicus Q62940 887 102376 T113 D P M S G V L T S V Q T K T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510045 844 95264 S104 G T A S V N L S N V L K N N G
Chicken Gallus gallus NP_001034349 924 104070 W104 G T A S V S L W N L L K N G G
Frog Xenopus laevis Q2TAS2 751 86306 F29 K N L V K K D F F R L P D S F
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 G43 F A K V V V D G S G Q C H S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0H4 949 107948 A133 G E R I I N L A H I L Q H Y N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 V87 D Q G F L G V V N V R V G D V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.1 98.7 90.7 N.A. 95.9 34 N.A. 87.9 80 36 35.5 N.A. 52.3 N.A. N.A. N.A.
Protein Similarity: 100 72.3 99.3 91.6 N.A. 97.9 49.7 N.A. 90.8 84.8 51.7 51.3 N.A. 65.5 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 20 N.A. 100 73.3 6.6 6.6 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 33.3 N.A. 100 86.6 20 26.6 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 50 0 0 0 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 17 0 0 9 0 0 17 0 0 0 0 0 9 9 0 % D
% Glu: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 9 0 0 0 9 9 0 0 0 0 0 9 % F
% Gly: 59 0 9 0 9 9 0 9 0 9 0 0 9 9 50 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 9 17 0 0 % H
% Ile: 0 0 9 9 9 0 0 0 0 9 9 0 0 0 9 % I
% Lys: 9 0 9 0 9 17 0 0 0 0 0 50 9 0 9 % K
% Leu: 0 0 9 0 17 0 67 0 9 17 67 0 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 50 0 0 59 0 0 0 59 42 9 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 0 9 0 0 0 0 9 0 0 0 17 9 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 9 9 0 0 9 0 % R
% Ser: 0 0 0 59 0 9 0 42 17 0 0 0 0 17 0 % S
% Thr: 0 59 0 0 0 0 0 9 0 0 0 9 0 9 9 % T
% Val: 0 0 0 17 59 17 9 9 0 59 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _