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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWP2
All Species:
25.45
Human Site:
Y348
Identified Species:
50.91
UniProt:
O00308
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00308
NP_008945.2
870
98912
Y348
D
P
R
G
R
F
Y
Y
V
D
H
N
T
R
T
Chimpanzee
Pan troglodytes
XP_519843
922
105197
Y399
D
D
R
R
R
V
Y
Y
V
D
H
N
T
R
T
Rhesus Macaque
Macaca mulatta
XP_001101869
870
98735
Y348
D
P
R
G
R
F
Y
Y
V
D
H
N
T
R
T
Dog
Lupus familis
XP_851140
922
104001
Y400
D
P
R
G
R
F
Y
Y
V
D
H
N
T
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBH0
870
98742
Y348
D
P
R
G
R
F
Y
Y
V
D
H
N
T
R
T
Rat
Rattus norvegicus
Q62940
887
102376
A352
P
D
V
Q
V
R
L
A
E
E
L
D
T
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510045
844
95264
E336
T
T
W
Q
R
P
T
E
E
Y
V
R
N
Y
E
Chicken
Gallus gallus
NP_001034349
924
104070
Y401
D
P
R
G
R
Y
Y
Y
V
D
H
N
T
R
T
Frog
Xenopus laevis
Q2TAS2
751
86306
Q259
D
L
P
E
G
Y
E
Q
R
T
T
Q
Q
G
Q
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Q273
Q
V
Y
F
L
H
T
Q
T
G
V
S
T
W
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
Y413
D
G
R
G
R
V
Y
Y
V
D
H
N
T
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
A317
P
P
V
N
G
A
A
A
A
A
F
A
A
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.1
98.7
90.7
N.A.
95.9
34
N.A.
87.9
80
36
35.5
N.A.
52.3
N.A.
N.A.
N.A.
Protein Similarity:
100
72.3
99.3
91.6
N.A.
97.9
49.7
N.A.
90.8
84.8
51.7
51.3
N.A.
65.5
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
13.3
N.A.
6.6
93.3
6.6
6.6
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
26.6
N.A.
6.6
100
13.3
13.3
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
17
9
9
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
17
0
0
0
0
0
0
0
59
0
9
0
0
0
% D
% Glu:
0
0
0
9
0
0
9
9
17
9
0
0
0
0
9
% E
% Phe:
0
0
0
9
0
34
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
0
50
17
0
0
0
0
9
0
0
0
9
9
% G
% His:
0
0
0
0
0
9
0
0
0
0
59
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
9
0
0
9
0
9
0
0
0
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
59
9
0
0
% N
% Pro:
17
50
9
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
17
0
0
0
17
0
0
0
9
9
0
9
% Q
% Arg:
0
0
59
9
67
9
0
0
9
0
0
9
0
67
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% S
% Thr:
9
9
0
0
0
0
17
0
9
9
9
0
75
9
50
% T
% Val:
0
9
17
0
9
17
0
0
59
0
17
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
0
17
59
59
0
9
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _