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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPK1A All Species: 14.24
Human Site: S123 Identified Species: 34.81
UniProt: O00322 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00322 NP_008931.1 258 28879 S123 T H R D Y M V S N P S L I T K
Chimpanzee Pan troglodytes XP_001159055 192 21871 E61 L W D R V M I E V G G V D R V
Rhesus Macaque Macaca mulatta XP_001096659 258 28748 S123 T H R D Y M V S S P S L I T K
Dog Lupus familis XP_541693 257 28721 S122 T H R D Y M V S N P S L I T K
Cat Felis silvestris
Mouse Mus musculus Q9D132 257 28835 S122 T H R D Y M V S N P S L I T K
Rat Rattus norvegicus Q566D0 260 29794 K123 F T T N L F L K Q M L M R Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509263 177 19180 F46 W I S I F T G F A F F L V G S
Chicken Gallus gallus XP_416567 193 21972 Y62 L K Q M L E R Y M K S D T D N
Frog Xenopus laevis NP_001086734 252 28497 N118 R D Y M I N S N V I K G Q M L
Zebra Danio Brachydanio rerio NP_001035332 250 27455 V119 L V G N S N L V K K Q M L Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.5 95.3 94.5 N.A. 93.8 38.4 N.A. 43.7 29 60 45.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 54.2 98 97.2 N.A. 98 59.2 N.A. 53.8 46.1 77.1 64.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 100 N.A. 100 0 N.A. 6.6 6.6 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 26.6 N.A. 20 13.3 6.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 40 0 0 0 0 0 0 0 10 10 10 0 % D
% Glu: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 10 10 0 10 0 10 10 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 0 0 10 10 10 0 10 0 % G
% His: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 10 0 10 0 0 10 0 0 40 0 0 % I
% Lys: 0 10 0 0 0 0 0 10 10 20 10 0 0 0 40 % K
% Leu: 30 0 0 0 20 0 20 0 0 0 10 50 10 0 10 % L
% Met: 0 0 0 20 0 50 0 0 10 10 0 20 0 10 0 % M
% Asn: 0 0 0 20 0 20 0 10 30 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 10 0 10 0 10 10 10 % Q
% Arg: 10 0 40 10 0 0 10 0 0 0 0 0 10 10 0 % R
% Ser: 0 0 10 0 10 0 10 40 10 0 50 0 0 0 10 % S
% Thr: 40 10 10 0 0 10 0 0 0 0 0 0 10 40 0 % T
% Val: 0 10 0 0 10 0 40 10 20 0 0 10 10 0 10 % V
% Trp: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 40 0 0 10 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _