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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPK1A All Species: 14.85
Human Site: Y120 Identified Species: 36.3
UniProt: O00322 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00322 NP_008931.1 258 28879 Y120 T S Y T H R D Y M V S N P S L
Chimpanzee Pan troglodytes XP_001159055 192 21871 V58 L T R L W D R V M I E V G G V
Rhesus Macaque Macaca mulatta XP_001096659 258 28748 Y120 T S Y T H R D Y M V S S P S L
Dog Lupus familis XP_541693 257 28721 Y119 T S Y T H R D Y M V S N P S L
Cat Felis silvestris
Mouse Mus musculus Q9D132 257 28835 Y119 T S Y T H R D Y M V S N P S L
Rat Rattus norvegicus Q566D0 260 29794 L120 R D F F T T N L F L K Q M L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509263 177 19180 F43 A G A W I S I F T G F A F F L
Chicken Gallus gallus XP_416567 193 21972 L59 N L F L K Q M L E R Y M K S D
Frog Xenopus laevis NP_001086734 252 28497 I115 F T H R D Y M I N S N V I K G
Zebra Danio Brachydanio rerio NP_001035332 250 27455 S116 R D Y L V G N S N L V K K Q M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.5 95.3 94.5 N.A. 93.8 38.4 N.A. 43.7 29 60 45.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 54.2 98 97.2 N.A. 98 59.2 N.A. 53.8 46.1 77.1 64.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 100 N.A. 100 0 N.A. 6.6 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 26.6 N.A. 13.3 20 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 10 10 40 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % E
% Phe: 10 0 20 10 0 0 0 10 10 0 10 0 10 10 0 % F
% Gly: 0 10 0 0 0 10 0 0 0 10 0 0 10 10 10 % G
% His: 0 0 10 0 40 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 10 10 0 10 0 0 10 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 10 10 20 10 0 % K
% Leu: 10 10 0 30 0 0 0 20 0 20 0 0 0 10 50 % L
% Met: 0 0 0 0 0 0 20 0 50 0 0 10 10 0 20 % M
% Asn: 10 0 0 0 0 0 20 0 20 0 10 30 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 10 0 10 0 % Q
% Arg: 20 0 10 10 0 40 10 0 0 10 0 0 0 0 0 % R
% Ser: 0 40 0 0 0 10 0 10 0 10 40 10 0 50 0 % S
% Thr: 40 20 0 40 10 10 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 10 0 40 10 20 0 0 10 % V
% Trp: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 50 0 0 10 0 40 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _