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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARNTL
All Species:
30.91
Human Site:
S590
Identified Species:
61.82
UniProt:
O00327
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00327
NP_001025443.1
626
68762
S590
M
I
D
N
D
Q
G
S
S
S
P
S
N
D
E
Chimpanzee
Pan troglodytes
XP_001171687
626
68743
S590
M
I
D
N
D
Q
G
S
S
S
P
S
N
D
E
Rhesus Macaque
Macaca mulatta
XP_001095200
626
68713
S590
M
I
D
N
D
Q
G
S
S
S
P
S
N
D
E
Dog
Lupus familis
XP_851850
634
69695
S598
M
I
E
N
D
Q
G
S
S
S
P
S
N
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTL8
632
69433
S596
M
I
D
N
D
Q
G
S
S
S
P
S
N
D
E
Rat
Rattus norvegicus
Q9EPW1
626
68597
S590
M
I
D
N
D
Q
G
S
S
S
P
S
N
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507514
398
44707
R363
K
F
V
F
V
D
Q
R
A
T
A
I
L
A
Y
Chicken
Gallus gallus
Q9I8T7
633
69419
S597
M
I
D
N
D
Q
G
S
S
S
P
S
N
D
E
Frog
Xenopus laevis
NP_001089024
627
68721
S591
M
T
E
T
E
H
G
S
S
S
P
S
N
D
E
Zebra Danio
Brachydanio rerio
Q9DG12
737
80954
N644
A
T
S
S
P
S
G
N
A
Y
S
N
L
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61734
413
47551
R378
T
T
Q
V
Y
R
F
R
C
K
D
N
S
Y
I
Honey Bee
Apis mellifera
XP_001121441
739
82052
V702
I
N
E
S
P
N
P
V
P
S
D
G
N
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.8
97.6
N.A.
97.3
98.2
N.A.
52.8
93.2
85.8
31.6
N.A.
35.2
42.6
N.A.
N.A.
Protein Similarity:
100
100
99.8
98.4
N.A.
97.7
98.8
N.A.
55.4
95
91
49.9
N.A.
48.5
55.6
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
0
100
66.6
6.6
N.A.
0
26.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
80
33.3
N.A.
20
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
17
0
9
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
59
9
0
0
0
0
17
0
0
75
0
% D
% Glu:
0
0
25
0
9
0
0
0
0
0
0
0
0
0
75
% E
% Phe:
0
9
0
9
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
75
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
59
0
0
0
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% L
% Met:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
59
0
9
0
9
0
0
0
17
75
0
9
% N
% Pro:
0
0
0
0
17
0
9
0
9
0
67
0
0
0
0
% P
% Gln:
0
0
9
0
0
59
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
17
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
17
0
9
0
67
67
75
9
67
9
0
0
% S
% Thr:
9
25
0
9
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
9
9
9
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _