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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC33A1
All Species:
22.73
Human Site:
S218
Identified Species:
38.46
UniProt:
O00400
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00400
NP_004724.1
549
60909
S218
G
Y
A
S
T
C
N
S
V
G
Q
T
A
G
Y
Chimpanzee
Pan troglodytes
XP_516831
549
60791
S218
G
Y
A
S
T
C
N
S
V
G
Q
T
A
G
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542846
551
60720
S219
G
Y
A
S
T
C
N
S
V
G
Q
T
A
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q99J27
550
61057
S218
G
Y
A
S
T
C
N
S
V
G
Q
T
A
G
Y
Rat
Rattus norvegicus
Q6AYY8
550
61083
S218
G
Y
A
S
T
C
N
S
V
G
Q
T
A
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516882
325
35699
A23
C
D
G
G
E
T
R
A
R
K
I
K
S
V
L
Chicken
Gallus gallus
XP_422831
546
59852
T218
T
C
N
S
V
G
Q
T
A
G
Y
F
L
G
N
Frog
Xenopus laevis
NP_001084638
538
60168
F218
Y
F
M
G
N
V
L
F
L
A
L
E
S
A
D
Zebra Danio
Brachydanio rerio
NP_957402
543
60268
V219
A
G
Y
F
L
G
N
V
L
F
L
A
L
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648921
525
59130
T223
P
L
E
D
G
M
I
T
L
P
R
F
L
W
F
Honey Bee
Apis mellifera
XP_391950
515
58206
G213
R
S
T
P
S
N
K
G
I
L
T
L
P
D
V
Nematode Worm
Caenorhab. elegans
NP_001122645
549
61317
Y226
F
L
R
S
K
E
N
Y
K
D
T
G
I
I
D
Sea Urchin
Strong. purpuratus
XP_794580
523
58139
E220
Y
L
R
W
E
P
Q
E
Q
G
I
V
T
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38318
560
62991
Y218
G
F
I
S
L
G
G
Y
M
K
F
S
G
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.1
N.A.
93.4
93
N.A.
50.6
81.4
72.1
70.6
N.A.
49.9
53
49.9
55.9
Protein Similarity:
100
99.8
N.A.
93.8
N.A.
96
95.8
N.A.
55.7
87.8
83.2
81.7
N.A.
67.9
67.7
66.8
72.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
20
0
6.6
N.A.
0
0
13.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
26.6
20
13.3
N.A.
26.6
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
36
0
0
0
0
8
8
8
0
8
36
8
0
% A
% Cys:
8
8
0
0
0
36
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
8
0
0
0
8
15
% D
% Glu:
0
0
8
0
15
8
0
8
0
0
0
8
0
8
0
% E
% Phe:
8
15
0
8
0
0
0
8
0
8
8
15
0
0
8
% F
% Gly:
43
8
8
15
8
22
8
8
0
50
0
8
8
43
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
8
0
15
0
8
8
0
% I
% Lys:
0
0
0
0
8
0
8
0
8
15
0
8
0
0
8
% K
% Leu:
0
22
0
0
15
0
8
0
22
8
15
8
22
8
15
% L
% Met:
0
0
8
0
0
8
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
8
8
50
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
8
0
8
0
0
0
8
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
15
0
8
0
36
0
0
0
0
% Q
% Arg:
8
0
15
0
0
0
8
0
8
0
8
0
0
0
0
% R
% Ser:
0
8
0
58
8
0
0
36
0
0
0
8
15
0
8
% S
% Thr:
8
0
8
0
36
8
0
15
0
0
15
36
8
0
0
% T
% Val:
0
0
0
0
8
8
0
8
36
0
0
8
0
8
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
15
36
8
0
0
0
0
15
0
0
8
0
0
0
36
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _