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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC33A1
All Species:
6.06
Human Site:
S285
Identified Species:
10.26
UniProt:
O00400
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00400
NP_004724.1
549
60909
S285
L
K
K
E
N
E
V
S
V
V
K
E
E
T
Q
Chimpanzee
Pan troglodytes
XP_516831
549
60791
S285
L
K
K
E
N
E
V
S
V
V
K
E
E
T
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542846
551
60720
V286
L
K
K
E
N
K
E
V
S
V
G
K
E
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99J27
550
61057
A285
L
K
K
E
N
R
E
A
S
I
V
K
E
E
T
Rat
Rattus norvegicus
Q6AYY8
550
61083
A285
L
K
K
E
T
R
E
A
S
V
V
K
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516882
325
35699
C90
M
P
A
V
L
A
F
C
L
L
I
L
T
A
K
Chicken
Gallus gallus
XP_422831
546
59852
K285
N
K
E
L
T
P
T
K
E
E
T
K
G
I
T
Frog
Xenopus laevis
NP_001084638
538
60168
Y285
T
Q
S
V
K
E
A
Y
G
L
L
L
N
I
V
Zebra Danio
Brachydanio rerio
NP_957402
543
60268
Q286
K
K
P
K
E
E
T
Q
G
V
K
E
T
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648921
525
59130
I290
P
V
Q
I
L
A
V
I
L
L
T
V
K
V
T
Honey Bee
Apis mellifera
XP_391950
515
58206
L280
K
I
I
I
V
F
L
L
T
A
K
I
G
F
S
Nematode Worm
Caenorhab. elegans
NP_001122645
549
61317
L293
V
A
E
S
Y
A
V
L
Y
K
I
L
K
L
K
Sea Urchin
Strong. purpuratus
XP_794580
523
58139
S287
F
L
V
I
V
I
T
S
K
M
G
Y
A
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38318
560
62991
R285
S
S
I
K
Y
I
Y
R
C
F
I
K
V
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.1
N.A.
93.4
93
N.A.
50.6
81.4
72.1
70.6
N.A.
49.9
53
49.9
55.9
Protein Similarity:
100
99.8
N.A.
93.8
N.A.
96
95.8
N.A.
55.7
87.8
83.2
81.7
N.A.
67.9
67.7
66.8
72.3
P-Site Identity:
100
100
N.A.
46.6
N.A.
40
40
N.A.
0
6.6
6.6
33.3
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
60
N.A.
60
53.3
N.A.
26.6
20
20
46.6
N.A.
33.3
13.3
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
22
8
15
0
8
0
0
8
15
8
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
15
36
8
29
22
0
8
8
0
22
36
22
0
% E
% Phe:
8
0
0
0
0
8
8
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
15
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
15
22
0
15
0
8
0
8
22
8
0
15
0
% I
% Lys:
15
50
36
15
8
8
0
8
8
8
29
36
15
0
29
% K
% Leu:
36
8
0
8
15
0
8
15
15
22
8
22
0
15
0
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
29
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
8
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
15
% Q
% Arg:
0
0
0
0
0
15
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
8
8
8
0
0
0
22
22
0
0
0
0
0
8
% S
% Thr:
8
0
0
0
15
0
22
0
8
0
15
0
15
15
36
% T
% Val:
8
8
8
15
15
0
29
8
15
36
15
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
8
8
8
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _