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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC33A1
All Species:
33.64
Human Site:
S541
Identified Species:
56.92
UniProt:
O00400
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00400
NP_004724.1
549
60909
S541
K
L
Q
D
E
G
S
S
S
W
K
C
K
R
N
Chimpanzee
Pan troglodytes
XP_516831
549
60791
S541
K
L
Q
D
E
G
S
S
S
W
K
C
K
R
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542846
551
60720
S543
K
L
Q
D
K
G
P
S
S
W
K
C
K
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99J27
550
61057
S542
K
L
Q
D
E
G
P
S
S
W
K
C
K
R
N
Rat
Rattus norvegicus
Q6AYY8
550
61083
S542
K
L
Q
D
E
G
P
S
S
W
K
C
K
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516882
325
35699
S317
K
L
Q
D
E
G
P
S
S
W
Q
C
K
R
V
Chicken
Gallus gallus
XP_422831
546
59852
S538
K
L
Q
D
E
G
Q
S
S
W
K
C
K
R
T
Frog
Xenopus laevis
NP_001084638
538
60168
S528
K
L
Q
D
E
G
Q
S
S
W
K
C
R
R
R
Zebra Danio
Brachydanio rerio
NP_957402
543
60268
S535
R
L
Q
E
E
S
P
S
A
W
H
C
R
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648921
525
59130
W517
Q
D
L
P
V
R
S
W
L
V
V
K
Q
K
S
Honey Bee
Apis mellifera
XP_391950
515
58206
V508
R
P
I
S
A
W
K
V
I
L
S
K
Q
N
R
Nematode Worm
Caenorhab. elegans
NP_001122645
549
61317
S538
Y
L
Q
K
I
P
R
S
Q
W
R
V
F
P
S
Sea Urchin
Strong. purpuratus
XP_794580
523
58139
R514
E
L
P
L
D
S
W
R
L
P
S
S
G
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38318
560
62991
L552
K
I
L
H
L
Q
S
L
P
I
S
S
W
R
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.1
N.A.
93.4
93
N.A.
50.6
81.4
72.1
70.6
N.A.
49.9
53
49.9
55.9
Protein Similarity:
100
99.8
N.A.
93.8
N.A.
96
95.8
N.A.
55.7
87.8
83.2
81.7
N.A.
67.9
67.7
66.8
72.3
P-Site Identity:
100
93.3
N.A.
80
N.A.
93.3
86.6
N.A.
80
86.6
80
40
N.A.
6.6
0
26.6
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
86.6
86.6
86.6
66.6
N.A.
33.3
13.3
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
65
0
0
8
% C
% Asp:
0
8
0
58
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
8
58
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
58
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
65
0
0
8
8
0
8
0
0
0
50
15
50
8
0
% K
% Leu:
0
79
15
8
8
0
0
8
15
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
15
% N
% Pro:
0
8
8
8
0
8
36
0
8
8
0
0
0
8
0
% P
% Gln:
8
0
72
0
0
8
15
0
8
0
8
0
15
0
0
% Q
% Arg:
15
0
0
0
0
8
8
8
0
0
8
0
15
65
15
% R
% Ser:
0
0
0
8
0
15
29
72
58
0
22
15
0
8
36
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% T
% Val:
0
0
0
0
8
0
0
8
0
8
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
8
8
8
0
72
0
0
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _